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首页> 外文期刊>Scandinavian journal of infectious diseases. >Staphylococcus aureus endocarditis in Danish intravenous drug users: high proportion of left-sided endocarditis.
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Staphylococcus aureus endocarditis in Danish intravenous drug users: high proportion of left-sided endocarditis.

机译：丹麦静脉吸毒者金黄色葡萄球菌性心内膜炎：高比例的左侧心内膜炎。

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摘要

In a retrospective study covering the years 1982-1989 episodes of Staphylococcus aureus endocarditis in 51 intravenous drug users were studied. Tricuspid involvement dominated (34/51), but the frequency of left-sided involvement (33.3%) was greater than in earlier reports. Involvement of both sides of the heart was not detected, but 27.8% of the left-sided endocarditis cases had multiple pulmonary infiltrates, indicating that some of them might have had a concomitant right-sided endocarditis. The 2 groups were compared: patients with left-sided endocarditis were significantly older and with a longer time of intravenous drug use. The complication rate was the same (44.1%) as was the duration of antibiotic treatment (median 42 days). In total, five patients underwent surgery, two (5.8%) due to right-sided failure and three (29.4%) because of left-sided endocarditis. The mortality of tricuspid endocarditis was low (2.9%), whereas 5 patients (29.4%) with left-sided involvement died. The patients who died were significantly older and had a shorter duration of symptoms before hospitalization.
机译：在一项涵盖1982-1989年的回顾性研究中，研究了51个静脉吸毒者的金黄色葡萄球菌心内膜炎的发作。三尖瓣受累占主导地位（34/51），但左侧受累频率（33.3％）大于早期报道。未检测到心脏两侧受累，但27.8％的左侧心内膜炎患者有多处肺部浸润，表明其中一些患者可能伴有右侧心内膜炎。比较了两组：左侧心内膜炎患者年龄较大，静脉内药物使用时间较长。并发症发生率与抗生素治疗持续时间（中位数42天）相同（44.1％）。共有5例患者接受了手术，其中2例（5.8％）因右侧衰竭而行手术，3例（29.4％）因左侧心内膜炎而行手术。三尖瓣心内膜炎的死亡率很低（2.9％），而左侧受累的5例患者（29.4％）死亡。死亡的患者年龄较大，住院前症状持续时间较短。

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