Activation of toll-like receptors by microbial lipoproteins.

Sieling PA; Modlin RL

首页> 外文期刊>Scandinavian journal of infectious diseases. >Activation of toll-like receptors by microbial lipoproteins.

【24h】

Activation of toll-like receptors by microbial lipoproteins.

机译：微生物脂蛋白激活toll样受体。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

In Drosophila, the Toll family of proteins are central to innate defense against microbial pathogens. Conserved throughout evolution, mammalian Toll-like receptors (TLRs) participate in innate immunity. TLRs mediate activation by microbial ligands including lipoproteins, resulting in the activation of IL-12 and nitric oxide synthase. Microbial lipoproteins also induce host cell apoptosis. In this manner, the ability of microbial lipoproteins to activate TLRs can contribute to host defense and immunopathology during infection.

机译：在果蝇中，蛋白质的Toll家族对于先天防御微生物病原体至关重要。在整个进化过程中保守，哺乳动物的Toll样受体（TLR）参与先天免疫。 TLR通过包括脂蛋白在内的微生物配体介导激活，导致IL-12和一氧化氮合酶激活。微生物脂蛋白还诱导宿主细胞凋亡。以这种方式，微生物脂蛋白激活TLR的能力可有助于感染期间的宿主防御和免疫病理学。

著录项

来源
《Scandinavian journal of infectious diseases.》 |2001年第2期|共4页
作者
Sieling PA; Modlin RL;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Bacteria; Immunity; Membrane Glycoproteins; Receptors; Cell Surface; Interleukin-12; 细菌; 免疫性; 膜糖蛋白类; 受体; 细胞表面;

机译：Bacteria;Immunity;Membrane Glycoproteins;Receptors;Cell Surface;Interleukin-12;细菌;免疫性;膜糖蛋白类;受体;细胞表面;

相似文献

外文文献
中文文献
专利

1. Activation of toll-like receptors by microbial lipoproteins. [J] . Sieling PA, Modlin RL Scandinavian journal of infectious diseases. . 2001,第2期

机译：微生物脂蛋白激活toll样受体。
2. Activation of toll-like receptors by microbial lipoproteins: role in host defense. [J] . Modlin RL The Journal of Allergy and Clinical Immunology . 2001,第4Suppla期

机译：微生物脂蛋白激活toll样受体：在宿主防御中的作用。
3. Microbial Amyloids Induce Interleukin 17A (IL-17A) and IL-22 Responses via Toll-Like Receptor 2 Activation in the Intestinal Mucosa [J] . Jessalyn H. Nishimori, Tiffanny N. Newman, Gertrude O. Oppong, Infection and immunity . 2012,第12期

机译：微生物淀粉样蛋白通过Toll样受体2激活肠粘膜诱导白介素17A（IL-17A）和IL-22反应。
4. Molecular mechanism for innate recognition of microbial products by toll-like receptors [C] . Kensuke Miyake Uehara Memorial Foundation Symposium on the Innate Immune System . 2005

机译：通过Toll样受体先天识别微生物产品的分子机制
5. The function, activation and inhibition of phosphatidic acid phosphohydrolase-1 and Group IVA phospholipase A2 in toll-like receptor-4 activated macrophages. [D] . Grkovich, Andrej. 2008

机译：Toll样受体4活化巨噬细胞中磷脂酸磷酸水解酶1和IVA组磷脂酶A2的功能，激活和抑制。
6. Microbial Amyloids Induce Interleukin 17A (IL-17A) and IL-22 Responses via Toll-Like Receptor 2 Activation in the Intestinal Mucosa [O] . Jessalyn H. Nishimori, Tiffanny N. Newman, Gertrude O. Oppong, 2012

机译：微生物淀粉样蛋白通过肠粘膜中的Toll样受体2激活诱导白介素17A（IL-17A）和IL-22反应。
7. Microbial Amyloids Induce Interleukin 17A (IL-17A) and IL-22 Responses via Toll-Like Receptor 2 Activation in the Intestinal Mucosa [O] . Jessalyn H. Nishimori, Tiffanny N. Newman, Gertrude O. Oppong, 2012

机译：微生物淀粉样蛋白诱导白细胞介素17a（IL-17a）和IL-22通过肠粘膜中的含量的受体2活化反应
8. Direct Detection of Microbial Infection Through Activation Coupling of the Toll-Like Receptors [R] . Beutler, B. 2004

机译：通过Toll样受体的激活偶联直接检测微生物感染

Activation of toll-like receptors by microbial lipoproteins.

摘要

著录项

相似文献

相关主题

期刊订阅