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首页> 外文期刊>Seminars in Gastrointestinal Disease >Clinical problems with developmental anomalies of the biliary tract.
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Clinical problems with developmental anomalies of the biliary tract.

机译：胆道发育异常的临床问题。

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摘要

Cholestatic jaundice defined as conjugated hyperbilirubinemia is a typical feature of neonatal liver disease. Biliary atresia is the most common disorder producing cholestasis during the first 2 months of life. Syndromic and non-syndromic paucity of the intralobular bile ducts and choledochal cysts can also present with cholestasis during early life. Liver dysfunction from obstruction of the biliary tree must be differentiated from numerous disorders affecting hepatocytes such as congenital infection and inborn errors of metabolism. Early recognition and a stepwise diagnostic evaluation of the cholestatic infant are essential in successfully treating many metabolic and infectious liver diseases of the infant as well as surgically relieving obstruction in patients with biliary atresia.
机译：胆汁淤积性黄疸定义为结合性高胆红素血症，是新生儿肝脏疾病的典型特征。胆道闭锁是生命的头两个月内最常见的胆汁淤积症。小叶内胆管和胆总管囊肿的综合征和非综合征性贫血在生命早期也可能出现胆汁淤积。胆道梗阻引起的肝功能障碍必须与影响肝细胞的多种疾病（例如先天性感染和先天性代谢错误）区分开来。胆汁淤积性婴儿的早期识别和逐步诊断评估对于成功治疗婴儿的许多代谢和感染性肝病以及通过手术缓解胆道闭锁患者的梗阻至关重要。

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