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首页> 外文期刊>Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology >Histologic examination of decellularized porcine intestinal submucosa extracellular matrix (CorMatrix) in pediatric congenital heart surgery
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Histologic examination of decellularized porcine intestinal submucosa extracellular matrix (CorMatrix) in pediatric congenital heart surgery

机译:小儿先天性心脏病手术中脱细胞猪肠粘膜下细胞外基质(CorMatrix)的组织学检查

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Background: CorMatrix is a decellularized porcine small intestinal submucosa extracellular matrix that has gained attention as a promising alternative to current materials used in cardiac repair. While animal models demonstrate integration of CorMatrix material with host tissue, the histologic characteristics of CorMatrix used in humans are less well-characterized. In this retrospective study, we report our experience with CorMatrix material used in pediatric congenital heart surgery and describe the histology of CorMatrix material and of surrounding native tissue in explanted specimens.
机译:背景:CorMatrix是一种脱细胞的猪小肠粘膜下细胞外基质,作为心脏修复中当前材料的一种有前途的替代方法,已引起人们的关注。虽然动物模型显示了CorMatrix材料与宿主组织的整合,但人类使用的CorMatrix的组织学特征却鲜为人知。在这项回顾性研究中,我们报告了在小儿先天性心脏手术中使用CorMatrix材料的经验,并描述了在植入标本中CorMatrix材料和周围自然组织的组织学。

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