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首页> 外文期刊>Seminars in neonatology: SN >Selected principles of perinatal-neonatal glucose metabolism.
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Selected principles of perinatal-neonatal glucose metabolism.

机译：围产期-新生儿葡萄糖代谢的选择原则。

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While the fetus is completely dependent on his/her mother for glucose and other nutrient transfer across the placenta, the adult is completely independent, especially one who is neither pregnant nor diabetic. The neonate is considered to be in a transition between the complete dependence of the fetus and the complete independence of the adult. The heterogeneity that is the hallmark of neonatal glucose metabolism is illustrated by the observation that maintenance of euglycaemia in the sick and/or low-birthweight neonate is especially difficult. This reinforces the concept that the neonate is vulnerable to carbohydrate disequilibrium. In this discussion, we shall first evaluate the definition of euglycaemia by considering the ranges for hypo- and hyperglycaemia. We shall also review the considerable literature that has been published on measurement of the rate of glucose production and the rate of glucose utilization in the neonate. This review highlights where further work is necessary to understand thedeveloping maturation (i.e. control) of glucose homeostasis in the neonate.
机译：尽管胎儿完全依赖他/她的母亲进行葡萄糖和其他营养素在胎盘上的转移，但是成年人是完全独立的，尤其是既没有怀孕也没有糖尿病的人。新生儿被认为是在胎儿的完全依赖与成人的完全独立之间的过渡。观察到的异质性是新生儿葡萄糖代谢的标志，因为观察到维持生病和/或低出生体重新生儿的正常血糖特别困难。这强化了新生儿容易遭受碳水化合物失衡的观念。在此讨论中，我们将首先通过考虑低血糖和高血糖的范围来评估正常血糖的定义。我们还将回顾有关测量新生儿葡萄糖生成速率和葡萄糖利用速率的大量文献。这篇综述强调了在哪里需要进一步的工作来了解新生儿葡萄糖稳态的发育成熟（即控制）。

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