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首页> 外文期刊>Seizure: the journal of the British Epilepsy Association >A study of 63 cases with eyelid myoclonia with or without absences: type of seizure or an epileptic syndrome?
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A study of 63 cases with eyelid myoclonia with or without absences: type of seizure or an epileptic syndrome?

机译：对63例眼睑肌阵挛症有无缺席的研究：癫痫发作类型或癫痫综合征？

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PURPOSE: Eyelid myoclonia and absences (EMA) induced by eye closure associated with brief, fast, and generalized paroxysms of polyspikes and waves was considered as an epileptic syndrome and a type of seizure as well. We analyzed the electroclinical features and evolution of EMA, and tried to determine if it represents a well-defined epileptic syndrome or a non-specific condition associated to other epilepsies. METHODS: Between June 1994 and June 2005, 63 patients who met diagnostic criteria of EMA were enrolled in the study and have been followed up to the present time. RESULTS: Two main groups could be identified. The first group was divided into two subgroups. One subgroup of 28 patients presented EMA associated with infrequent generalized tonic-clonic seizures (GTCS), and the other 1 of 9 patients presented early-onset EMA refractory to antiepileptic drugs (AEDs), associated or not with GTCS and mental retardation. Four of them had self-induced seizures. The second group included 26 patients with EMA associated with GTCS and/or massive myoclonias, or GTCS induced by intermittent photic stimulation. All these patients had electroclinical features compatible with idiopathic generalized epilepsies. CONCLUSION: In the first group, EMA should be considered as a photosensitive idiopathic epileptic syndrome. A subgroup of early-onset of EMA refractory to AEDs, associated or not with GTCS and mental retardation should also be considered as a variant or a distinct photosensitive idiopathic epileptic syndrome. Finally, in the second group EMA may correspond to a type of seizures in idiopathic generalized epilepsies.
机译：目的：闭眼引起的眼睑肌阵挛和失神（EMA）与多发，短波和短波发作有关，被认为是一种癫痫综合症，也是一种癫痫发作。我们分析了EMA的电临床特征和演变，并试图确定它是否代表定义明确的癫痫综合征或与其他癫痫相关的非特异性疾病。方法：在1994年6月至2005年6月之间，共有63例符合EMA诊断标准的患者入选了该研究，并进行了随访。结果：可以确定两个主要群体。第一组分为两个子组。 28例患者中的一个亚组表现为EMA与罕见的广泛性强直阵挛性癫痫发作（GTCS）相关，而9例患者中的另外1例表现为抗癫痫药物（AED）难治的早期发作EMA，与或不与GTCS和智力障碍相关。他们中有四个患有自发性癫痫发作。第二组包括26例EMA与GTCS和/或大肌阵挛相关的患者，或由间歇性光刺激引起的GTCS。所有这些患者均具有与特发性全身性癫痫兼容的电临床特征。结论：在第一组中，EMA应被视为光敏性特发性癫痫综合征。 AED难治性EMA的早期发作亚组，无论是否与GTCS和智力低下有关，也应被视为变异或明显的光敏性特发性癫痫综合征。最后，在第二组中，EMA可能对应于特发性全身性癫痫发作的一种。

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