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首页> 外文期刊>Sexual medicine reviews. >Prevalence of Female Sexual Dysfunction Among Premenopausal Women: A Systematic Review and Meta-Analysis of Observational Studies
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Prevalence of Female Sexual Dysfunction Among Premenopausal Women: A Systematic Review and Meta-Analysis of Observational Studies

机译：绝经前女性中女性性功能障碍的患病率：观察性研究的系统评价和荟萃分析

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Introduction: Epidemiologic research in female sexual dysfunction (FSD) has gained momentum in recent years, particularly in clinical populations and in menopausal women. However, sexual dysfunction also affects premenopausal women in general populations. Previous literature reviews have been unable to quantify the burden of FSD in general populations. This has been due in part to different definitions of dysfunction, heterogeneous study design, and the wide variety of measurement tools used.Aim: To provide a meta-analytical estimate of the prevalence of FSD in premenopausal women.Methods: Observational studies that assessed the prevalence of FSD in premenopausal women were systematically sought in relevant databases (January 2000 through July 2014). Publications that reported the prevalence rate for at least one domain of FSD were included. A meta-analysis of prevalence rates was performed and a meta-regression was used to analyze factors of study design.Main Outcome Measures: Estimated prevalence rates of FSD and its domains (hypoactive sexual desire disorder, sexual aversion disorder, female sexual arousal disorder, lubrication difficulties, female orgasmic disorder, and pain disorders).Results: After screening 9,292 results, 440 publications were retrieved for full-text review. Of these, 135 studies were included in the systematic review. Ninety-five of these studies were assessed further in a meta-analysis. There was substantial heterogeneity among studies. The prevalence of FSD in premenopausal women was estimated to be 40.9% (95% CI = 37.1—44.7, I2 = 99.0%). Prevalence rates of individual sexual disorders ranged from 20.6% (lubrication difficulties) to 28.2% (hypoactive sexual desire disorder). Further analyses showed significantly higher rates of FSD in studies in Africa, studies that used non-validated assessment tools, and studies without pharmaceutical funding.Conclusion: Prevalence estimates of FSD vary substantially. Nonetheless, results show that FSD is a significant public health problem that affects 41% of premenopausal women around the globe. More research and improved standardization are needed in this field.
机译：简介：近年来，女性性功能障碍（FSD）的流行病学研究得到了发展，特别是在临床人群和绝经期妇女中。但是，性功能障碍也影响了普通人群中的绝经前妇女。先前的文献综述无法量化普通人群中FSD的负担。这部分是由于功能障碍的定义不同，研究设计的多样性以及所使用的测量工具种类繁多所致。目的：提供对绝经前妇女FSD患病率的荟萃分析。方法：观察性研究在相关数据库中（2000年1月至2014年7月）系统地调查了绝经前妇女FSD的患病率。包括报告了至少一个FSD结构域患病率的出版物。对患病率进行荟萃分析，并使用荟萃回归分析研究设计的因素。主要结果指标：FSD及其领域（低性欲障碍，性厌恶症，女性性唤起障碍，结果：筛选了9,292个结果后，检索了440篇出版物进行全文审查。其中，有135项研究被纳入系统评价。在荟萃分析中对其中的九十五项研究进行了进一步评估。研究之间存在很大的异质性。绝经前女性FSD的患病率估计为40.9％（95％CI = 37.1-44.7，I2 = 99.0％）。个体性疾病的患病率从20.6％（润滑困难）到28.2％（性欲减退）不等。进一步的分析表明，在非洲的研究，使用未经验证的评估工具的研究以及没有药物资助的研究中，FSD的发生率明显较高。结论：FSD的患病率估计存在很大差异。尽管如此，结果表明，FSD是一个重大的公共卫生问题，影响了全球41％的绝经前妇女。在这一领域需要更多的研究和改进的标准化。

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