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首页> 外文期刊>International Journal for Vitamin and Nutrition Research: Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung >Effect of daily and intermittent iron supplementation on iron status of high school girls.
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Effect of daily and intermittent iron supplementation on iron status of high school girls.

机译：每日和间歇补铁对高中女生铁质状况的影响。

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摘要

This experimental study was designed to investigate the effects of daily versus intermittent iron supplementation on iron status of high school girls in Zahedan and Rasht cities in 1996-1997. The subjects were selected randomly from among students of grades 1-3 of four high schools in each city. Anemia was determined by measuring hematological indices. 260 anemic and a similar number of non-anemic subjects of 4 high schools were selected and allocated randomly to 4 treatment groups. During a 3-month period, the test groups were given 150 mg ferrous sulfate tablets (50 mg Fe). Subjects in group 1 received a daily dose, groups 2 & 3 received twice or once weekly doses respectively. The control group received no iron supplement. For these subjects, in addition to hematological indices biochemical iron indices were measured in the beginning and at the end of the study. The increases in hemoglobin concentration in anemic subjects were not significantly different among supplemented groups but were different from the control group (p < 0.00001). Among anemic subjects, changes in serum ferritin levels in 3 supplemented groups were significantly different from the control group. Serum ferritin in Group 1 was also increased to a greater extent than groups 2 and 3 (P < 0.00001). It is concluded that over the study period a weekly iron dose was as effective as a daily dose in treating anemia but the daily dose was more effective in improving iron stores than a weekly dose in the short run.
机译：这项实验性研究旨在调查每日补铁与间歇补铁对Zahedan和Rasht市1996-1997年高中女生铁状况的影响。从每个城市的四所中学的1-3年级学生中随机选择受试者。通过测量血液学指标确定贫血。选择了4所中学的260名贫血和非贫血的非贫血科目，并将其随机分配给4个治疗组。在三个月的时间内，给测试组服用150毫克硫酸亚铁片（50毫克铁）。第1组的受试者接受每日剂量，第2和3组的受试者分别接受两次或每周一次。对照组没有补铁。对于这些受试者，除了血液学指标外，还在研究的开始和结束时还测量了生化铁的指标。贫血受试者中血红蛋白浓度的增加在补充组之间无显着差异，但与对照组不同（p <0.00001）。在贫血受试者中，三个补充组的血清铁蛋白水平变化与对照组有显着差异。第1组的血清铁蛋白含量也比第2组和第3组更高（P <0.00001）。可以得出结论，在研究期内，每周一次的铁剂剂量与治疗贫血的每日剂量一样有效，但在短期内，每天一次的铁剂剂量比每周一次的剂量在改善铁存储方面更有效。

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