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首页> 外文期刊>Separation and Purification Technology >Improvement of process productivity and product purity by the application of a membrane phase contactor in enzymatic conversions
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Improvement of process productivity and product purity by the application of a membrane phase contactor in enzymatic conversions

机译：通过在酶促转化中应用膜相接触器来提高工艺生产率和产品纯度

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摘要

By applying a porous membrane that keeps interface and protects two adjacent phases against dispersion,a fully controllable equipment to carry out (bio)chemical reactions is obtained.A membrane phase contactor with extended interfacial area and almost arbitrary phase ratio and broad range of phase flows enables an intensification of the process of reagent mass transport that could have an influence on the rate and conversion degree in biochemical transformations.This results in obtaining high process productivity and purity of the product isolated from one of the phases separated by the membrane.Additionally,the (bio)catalyst can be concentrated in the zone of high substrate concentration through an oriented immobilization of the (bio)catalyst on the surface of membrane in the form of a hydrated gel layer.Such process solution enables full integration of substrate mass transport rate with the rate of its transformation,which ensures exceptionally high purity of the reaction products in the receiving phase free of the substrate and catalyst.
机译：通过使用保持界面并保护两个相邻相免受分散的多孔膜，可以获得进行（生物）化学反应的完全可控的设备。膜相接触器具有扩展的界面面积，几乎任意的相比和宽范围的相流可以增强试剂的质量传输过程，这可能会影响生化转化的速率和转化程度，从而获得高工艺生产率和从被膜分离的某一相中分离出的产物的纯度。通过将（生物）催化剂以水合凝胶层的形式定向固定在膜表面上，可以将（生物）催化剂浓缩在高底物浓度的区域中。转化率高，可确保反应产物的纯度极高接收相不含底物和催化剂。

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