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Removal of sodium ion from bile acid solution using diffusional dialysis with cation exchange membrane

机译：阳离子交换膜扩散渗析法从胆汁酸溶液中去除钠离子

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The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution.These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride>sodiumtaurocholate>sodium cholate systems in all cases.In the sodium cholate and sodium taurocholate systems,the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution.This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation.Using diffusional dialysis,7.3% of sodium ion was removed from rat serum.Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P<0.05;correlation coefficient=-0.606).
机译：基于非平衡热力学研究了钠离子通过CM1阳离子交换膜的行为，通过导电和扩散膜渗透性从胆汁酸溶液中去除钠离子，这些钠离子的膜渗透性按幅度顺序为氯化钠>牛磺胆酸钠>钠在胆酸钠和牛磺胆酸钠体系中，导电膜渗透性与浓度相关的曲线在每种胆汁酸溶液的初级胶束形成浓度附近均显示出梯度的明显变化，这归因于胆汁酸阴离子根据胶束形成的膜/溶液分布。通过扩散渗析，从大鼠血清中去除了7.3％的钠离子。钠离子随着大鼠血清中总胆汁酸浓度的增加而显着降低（P <0.05;相关性系数= -0.606）。

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