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Effect of temperature on separation of purine and pyrimidine bases on novel chelating resin

机译:温度对新型螯合树脂分离嘌呤和嘧啶碱基的影响

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摘要

The novel chelating resin poly-bis [4-(4'-biphenyl)oxamidine]-diaminoglyoxime (PLH_2) has been modified as ligand-excchange material with Co(II). The possibility of using PLH_2 as ligand exchanger in the chromatographic separation of nucleic acid bases and nucleosides has been studied at various temperaturs. PLH_2 offers the advantage of combining high sorption capacity with high selectivity for the ligands. It has a strong driving force for ligand sorption. Ligand-exchange chromatography on Co(II)-loaded funcctionalized. PLH_2 can be a useful alternative method for separation of nucleic acid bases and nucleosides.
机译:新型螯合树脂聚双[4-(4'-联苯)恶ox]-二氨基乙二肟(PLH_2)已被Co(II)改性为配体交换材料。已经在各种温度下研究了在核酸碱基和核苷色谱分离中使用PLH_2作为配体交换剂的可能性。 PLH_2具有将高吸附能力与对配体的高选择性相结合的优势。它具有强大的配体吸附驱动力。载有Co(II)的功能上的配体交换色谱。 PLH_2是分离核酸碱基和核苷的有用替代方法。

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