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Extraction of trans-resveratrol from red wine and optimization by response surface methodology

机译:从红酒中提取反式白藜芦醇并通过响应面法进行优化

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The optimization of liquid-liquid extraction of resveratrol from wine by organic solvent was investigated using a Doehlert design. Preliminary experiments were conducted to choose the solvent used for the experimental design. Two parameters were analysed: the composition of the binary solvent mixture and the solution/solvent ratio. The best result was obtained by superimposing the isoresponses of selectivity and yield. The optimum operating conditions for extraction were: (i) a solvent mixture of cyclohex-ane/pentanol with a weight ratio of 40/60 and (ii) a solution/solvent ratio of 30/70. Under these conditions, the yield is above 95% for a selectivity of about 6.6‰.
机译:使用Doehlert设计研究了用有机溶剂从酒中液-液提取白藜芦醇的优化方法。进行了初步实验以选择用于实验设计的溶剂。分析了两个参数:二元溶剂混合物的组成和溶液/溶剂的比例。通过叠加选择性和产率等反应获得最佳结果。提取的最佳操作条件为:(i)环己烷/戊醇的重量比为40/60的溶剂混合物,和(ii)溶液/溶剂的比值为30/70。在这些条件下,对于约6.6‰的选择性,产率高于95%。

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