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首页> 外文期刊>Cardiovascular revascularization medicine: including molecular interventions >'Mother-in-child' thrombectomy technique: A novel and effective approach to decrease intracoronary thrombus burden in acute myocardial infarction
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'Mother-in-child' thrombectomy technique: A novel and effective approach to decrease intracoronary thrombus burden in acute myocardial infarction

机译：“母婴”血栓切除术：减轻急性心肌梗死冠状动脉内血栓负担的新颖有效方法

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Background: The presence of large thrombus burden in patients presenting with acute myocardial infarction (AMI) is common and associated with poor prognosis. This study aimed to describe the feasibility and safety of the novel 'mother-in-child' thrombectomy (MCT) technique in patients presenting with AMI and large thrombus burden undergoing percutaneous coronary intervention (PCI). Methods: We studied 13 patients presenting with AMI who underwent PCI with persistent large intracoronary thrombus after standard thrombectomy. The procedure was performed using a 5. F 'Heartrail II-ST01' catheter (Terumo Medical) into a 6. F guiding system. Angiographic assessment of thrombus burden and coronary flow was obtained at baseline, immediately after thrombectomy and at the end of the procedure. Results: The mean age was 55.9??13.0 years and involved mostly males (76.9%). All patients underwent PCI via radial approach. Following MCT Thrombolysis In Myocardial Infarction (TIMI) flow improved by 2 or more degrees in 11 patients (84.5%), while visible angiographic thrombus was reduced in 11 patients (84.5%). In the final angiogram, normal TIMI flow was restored in 11 patients (84.5%), with normal myocardial 'blush' in 7 patients (53.8%) and total clearance of a visible thrombus in 7 patients (53.8%). Overall, 6 patients received thrombectomy as 'stand-alone' procedure. All patients were discharged alive after a mean of 5.6??2 days. Conclusion: This initial report suggests that significant reduction in thrombus burden and improvement of the coronary flow can be safely achieved in patients presenting with AMI and large thrombus burden by using the novel MCT technique. ? 2013 Elsevier Inc.
机译：背景：急性心肌梗死（AMI）患者存在大量血栓负担，且预后不良。这项研究旨在描述新型“母婴”血栓切除术（MCT）技术在患有AMI和大量血栓负担的患者中接受经皮冠状动脉介入治疗（PCI）的可行性和安全性。方法：我们研究了13例患有AMI的患者，这些患者在标准血栓切除术后接受了PCI合并持续性大冠状动脉内血栓。该程序是使用5. F的“ Heartrail II-ST01”导管（Terumo Medical）插入6. F引导系统中进行的。在基线，血栓切除后立即和手术结束时进行了血栓负荷和冠状动脉血流的血管造影评估。结果：平均年龄为55.9〜13.0岁，男性占多数（76.9％）。所有患者均通过radial骨入路接受PCI。继发于MCT的心肌梗塞溶栓（TIMI）后，11例患者（84.5％）的血流改善了2度或更多，而11例患者（84.5％）的可见血管造影血栓减少了。在最终的血管造影中，11例患者（84.5％）恢复了正常的TIMI血流，7例患者（53.8％）出现了正常的心肌“脸红”，7例患者（53.8％）可见血栓的总清除率。总体上，有6例患者以“独立”程序接受了血栓切除术。所有患者平均5.6〜2天后均存活。结论：该初步报告表明，通过使用新型MCT技术，可以在患有AMI和大血栓负担的患者中安全地显着减少血栓负担并改善冠状动脉血流。 ？ 2013爱思唯尔公司

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