Long-term efficacy of B cell depletion therapy on lung and skin involvement in diffuse systemic sclerosis

Bosello Silvia L.; De Luca Giacomo; Rucco Manuela; Berardi Giorgia; Falcione Matteo; Danza Francesco Maria; Pirronti Tommaso; Ferraccioli Gianfranco

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Long-term efficacy of B cell depletion therapy on lung and skin involvement in diffuse systemic sclerosis

机译：B细胞耗竭疗法对弥漫性全身性硬化症的肺和皮肤受累的长期疗效

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Objectives: To assess the long-term efficacy and safety of single and multiple courses of rituximab therapy in systemic sclerosis (SSc) patients with and without lung disease.

机译：目的：评估单次或多次疗程利妥昔单抗治疗在有或没有肺部疾病的系统性硬化症（SSc）患者中的长期疗效和安全性。

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《Seminars in Arthritis and Rheumatism》 |2015年第4期|共9页
作者
Bosello Silvia L.; De Luca Giacomo; Rucco Manuela; Berardi Giorgia; Falcione Matteo; Danza Francesco Maria; Pirronti Tommaso; Ferraccioli Gianfranco;
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正文语种 eng
中图分类免疫性疾病;
关键词
Systemic sclerosis; CD20 depletion therapy; Lung involvement; Skin fibrosis; B cells;

机译：系统性硬化;CD20耗竭疗法;肺受累;皮肤纤维化;B细胞;

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专利

1. Long-term efficacy of B cell depletion therapy on lung and skin involvement in diffuse systemic sclerosis [J] . Bosello Silvia L., De Luca Giacomo, Rucco Manuela, Seminars in Arthritis and Rheumatism . 2015,第4期

机译：B细胞耗竭疗法对弥漫性全身性硬化症的肺和皮肤受累的长期疗效
2. B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin [J] . Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, Arthritis Research . 2012,第3期

机译：弥漫性全身性硬化症患者的B细胞耗竭疗法会导致PDGFR表达和皮肤梭形细胞激活明显减少
3. B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial. [J] . Bosello S, De Santis M, Lama G, Arthritis research & therapy. . 2010,第2期

机译：弥漫性进行性系统性硬化中的B细胞耗竭：长达36个月的开放标签随访研究中的安全性，皮肤评分修改和IL-6调节。
4. The clinical efficacy of transfusion of cytokine-induced killer cells combined with chemotherapy and XiaoJi decoction in patients with stage IIIB/IV non-small cell lung cancer [C] . Liuning Li, Jiaying Liu, Xiaoshu Chai, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：细胞因子诱导的杀伤细胞输注结合化学疗法和消积汤治疗IIIB / IV期非小细胞肺癌的临床疗效
5. From mesenchymal stem cell therapy to discovery of drug therapy for systemic sclerosis. [D] . Chen, Chider. 2014

机译：从间充质干细胞疗法到系统性硬化症药物疗法的发现。
6. B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin [O] . Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, 2012

机译：弥漫性全身性硬化症患者的B细胞耗竭疗法会导致PDGFR表达和皮肤梭形细胞激活明显减少
7. B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin [O] . Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, 2012

机译：弥漫性全身性硬化症患者的B细胞耗竭疗法会导致PDGFR表达和皮肤梭形细胞激活明显减少

Long-term efficacy of B cell depletion therapy on lung and skin involvement in diffuse systemic sclerosis

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