Human neuroblastoma stem cells.

Ross RA; Spengler BA

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Human neuroblastoma stem cells.

机译：人神经母细胞瘤干细胞。

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Human neuroblastoma is an embryonic cancer of the neural crest. Cellular heterogeneity is a characteristic feature of both tumors and derived cell lines. Recent studies have revealed that both cell lines and tumors contain cancer stem cells. In culture, these cells are self-renewing, multipotent, and highly malignant; in tumors their frequency correlates with a worse prognosis. Their identification and characterization should now permit a targeted approach to more effective treatment of this often fatal childhood cancer.

机译：人神经母细胞瘤是神经c的胚胎癌。细胞异质性是肿瘤和衍生细胞系的特征。最近的研究表明，细胞系和肿瘤均含有癌干细胞。在培养中，这些细胞具有自我更新能力，多能性和高度恶性。在肿瘤中，它们的频率与更差的预后相关。他们的鉴定和表征现在应该允许有针对性的方法来更有效地治疗这种经常致命的儿童期癌症。

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来源
《Seminars in cancer biology》 |2007年第3期|共7页
作者
Ross RA; Spengler BA;
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正文语种 eng
中图分类肿瘤学;
关键词
Stem Cells; Neuroblastoma; Human; Malignant Neoplasms; 干细胞; 神经母细胞瘤;

机译：Stem Cells;Neuroblastoma;Human;Malignant Neoplasms;干细胞;神经母细胞瘤;

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专利

1. An alternative in vivo system for testing angiogenic potential of human neuroblastoma cells. [J] . Mangieri D, Nico B, Coluccia AM, Cancer letters . 2009,第2期

机译：用于测试人神经母细胞瘤细胞血管生成潜力的替代体内系统。
2. Human neuroblastoma stem cells. [J] . Ross RA, Spengler BA Seminars in cancer biology . 2007,第3期

机译：人神经母细胞瘤干细胞。
3. Regulation of the cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: a comparative study of human neuroglioma and neuroblastoma cells. [J] . Moolwaney AS, Igwe OJ Brain research. Molecular brain research . 2005,第1a2期

机译：白细胞介素-1β通过有丝分裂原激活的蛋白激酶信号传导通路对环氧合酶2系统的调节：人类神经胶质瘤和神经母细胞瘤细胞的比较研究。
4. A System for Accurate and Sensitive Measurements of Non-Human Glycoprotein Modifications on Human Embryonic Stem Cells. [C] . W. Travis Berggren, Kevin R. Conard, Tenneille E. Ludwig, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：一种用于对人胚胎干细胞的非人糖蛋白修饰的准确和敏感测量的系统。
5. Studies on the Anti-tumor Activities and Action Mechanisms of Banlangen Alkaloids on Human Neuroblastoma Cells. [D] . Liao, Xuemei. 2013

机译：板蓝根生物碱对人神经母细胞瘤细胞的抗肿瘤活性及其作用机制的研究。
6. Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells. [O] . X Li, P De Sarno, L Song, 1998

机译：过氧亚硝酸盐调节人神经母细胞瘤SH-SY5Y细胞中的酪氨酸磷酸化和磷酸肌醇信号转导：在人类1321N1星形细胞瘤细胞中的减弱作用。
7. Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells. [O] . Yoona Seo, Yoo-Sun Kim, Kyung Eun Lee, 2017

机译：人神经母细胞瘤细胞中苦味受体Tas2R8和Tas2R10的抗癌干细胞和抗侵袭活性。
8. Production of a Nervous-System-Specific Protein (14-3-2) BY Human Neuroblastoma Cells in Culture. [R] . herschman,harvey r. lerner,michael p. 1972

机译：通过培养的人神经母细胞瘤细胞产生神经系统特异性蛋白质（14-3-2）。

Human neuroblastoma stem cells.

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