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首页> 外文期刊>Sexually Transmitted Infections >Sexually transmitted infections and vaginal douching in a population of female sex workers in Nairobi, Kenya.
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Sexually transmitted infections and vaginal douching in a population of female sex workers in Nairobi, Kenya.

机译：肯尼亚内罗毕的一群性工作者中的性传播感染和阴道冲洗。

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OBJECTIVE: To assess the association between vaginal douching and sexually transmitted infections (STI) among a group of female sex workers (FSWs) in Nairobi, Kenya. METHODS: This study was part of a randomised, placebo controlled trial of monthly prophylaxis with 1 g of azithromycin to prevent STIs and HIV infection in a cohort of Nairobi FSWs. Consenting women were administered a questionnaire and screened for STIs. RESULTS: The seroprevalence of HIV-1 among 543 FSWs screened was 30%. HIV infection was significantly associated with bacterial vaginosis (BV), trichomoniasis, gonorrhoea, and the presence of a genital ulcer. Regular douching was reported by 72% of the women, of whom the majority inserted fluids in the vagina, generally after each sexual intercourse. Water with soap was the fluid most often used (81%), followed by salty water (18%), water alone (9%), and a commercial antiseptic (5%). Douching in general and douching with soap and water were significantly associated with bacterial vaginosis (p = 0.05 and p = 0.04 respectively). There was a significant trend for increased frequency of douching and higher prevalence of BV. There was no direct relation observed between douching and risk for HIV infection or other STIs. CONCLUSION: The widespread habit of douching among African female sex workers was confirmed. The association between vaginal douching and BV is of concern, given the increased risk of HIV infection with BV, which has now been shown in several studies. It is unclear why we could not demonstrate a direct association between douching and HIV infection. Further research is required to better understand the complex relation between douching, risk for bacterial vaginosis, and risk for HIV and other STIs.
机译：目的：评估肯尼亚内罗毕一群女性性工作者（FSW）的阴道冲洗与性传播感染（STI）之间的关联。方法：这项研究是一项随机，安慰剂对照试验的一部分，该试验为内罗毕FSW人群每月预防性用1 g阿奇霉素预防STIs和HIV感染。对同意的妇女进行问卷调查并筛查性传播感染。结果：在筛选的543例FSW中，HIV-1的血清阳性率为30％。 HIV感染与细菌性阴道病（BV），滴虫，淋病和生殖器溃疡显着相关。据报告，有72％的妇女会定期冲洗，通常在每次性交之后，她们中的大多数会将液体注入阴道。加肥皂的水是最常用的液体（81％），其次是咸水（18％），仅水（9％）和商业防腐剂（5％）。一般而言，加液和用肥皂和水冲洗与细菌性阴道病显着相关（分别为p = 0.05和p = 0.04）。有一种显着的趋势是洗牙频率增加和BV患病率更高。在冲洗和感染艾滋病毒或其他性传播感染的风险之间没有直接关系。结论：证实了在非洲女性性工作者中普遍使用洗牙的习惯。考虑到阴道灌洗与BV之间的关联是令人关注的，考虑到HIV感染BV的风险增加，现已在多项研究中表明。目前尚不清楚为什么我们不能证明冲洗和艾滋病毒感染之间有直接联系。需要进一步研究以更好地了解冲洗，细菌性阴道病风险以及HIV和其他性传播感染风险之间的复杂关系。

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