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Polycystic Ovary Syndrome, Obesity, and Pregnancy

机译:多囊卵巢综合症,肥胖与妊娠

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to one in five reproductive-aged women. It is underpinned by insulin resistance and hyper-androgenism and is associated with metabolic, reproductive, and psychological features. Women with PCOS have higher rates of obesity and central adiposity compared with women without PCOS, and weight strongly influences prevalence and clinical severity of PCOS. Women with PCOS may have subfertility and women should be aware of factors affecting fertility, in particular the impact of obesity and age. Once pregnant, women with PCOS have significantly increased risk of pregnancy-related complications including gestational diabetes, hypertensive disorders, premature delivery, and delivery by cesarean section. The offspring of women with PCOS may have increased risk of congenital abnormalities and hospitalization in childhood. Clinicians should be aware of the increased risk and screen, prevent, and manage accordingly.
机译:多囊卵巢综合征(PCOS)是一种常见的内分泌疾病,影响多达五分之一的育龄妇女。它以胰岛素抵抗和雄激素过多为基础,并与代谢,生殖和心理功能有关。与没有PCOS的女性相比,患有PCOS的女性肥胖和中央肥胖的发生率更高,而且体重强烈影响PCOS的患病率和临床严重程度。患有PCOS的女性可能会生育不足,因此女性应意识到影响生育的因素,尤其是肥胖和年龄的影响。一旦怀孕,患有PCOS的妇女会明显增加与妊娠有关的并发症的风险,包括妊娠糖尿病,高血压疾病,早产和剖宫产。患有PCOS的女性的后代可能会增加儿童先天性异常和住院的风险。临床医生应意识到增加的风险并进行筛查,预防和相应处理。

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