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首页> 外文期刊>Biomaterials >BLOOD PERFUSION AND REMODELLING ACTIVITY IN CANINE TIBIAL DIAPHYSIS AFTER FILLING WITH A NEW BONE CEMENT COMPARED TO BONE WAX AND POLY(METHYL METHACRYLATE) CEMENT
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BLOOD PERFUSION AND REMODELLING ACTIVITY IN CANINE TIBIAL DIAPHYSIS AFTER FILLING WITH A NEW BONE CEMENT COMPARED TO BONE WAX AND POLY(METHYL METHACRYLATE) CEMENT

机译：填充与蜡和聚甲基丙烯酸甲酯相比的新型骨水泥充填后，胫骨干PHY骨的血液灌注和重塑活性

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Six dogs each had one tibia filled with standard poly(methyl methacrylate) (PMMA) bone cement and the contralateral tibia filled with a new methyl methacrylate-n-decyl methacrylate-isobornyl methacrylate (MMA-DMA-IBMA) bone cement (Boneloc(R)) with lowered polymerization heat and monomer leakage, An additional six dogs each had one tibia filled with MMA-DMA-IBMA and the contralateral tibia filled with bone wax. There was a higher diaphyseal blood flow, measured with a microsphere technique, in the legs filled with MMA-DMA-IBMA than in those filled with PMMA. The wax-filled bones presented higher blood perfusion than those with MMA-DMA-IBMA. We found a tendency towards higher (99m)technetium-labelled methylene diphosphonate ((99m)TcMDp) uptake, and autoradiograms revealed a tendency towards larger subperiosteal apposition and more blackening, both at the subperiosteal apposition and the cortex, in the bones filled with new bone cement in the first series, but in wax-filled bone in the second series. it is concluded that the new bone cement, compared to standard acrylic bone cement, seems to inhibit the vascular response and bone remodelling activity less, making earlier remodelling possible. However, the new bone cement still seems to inhibit bone blood perfusion compared to bone wax. [References: 17]
机译：六只狗各有一个胫骨，充满标准的聚甲基丙烯酸甲酯（PMMA）骨水泥，对侧胫骨，充满新的甲基丙烯酸甲酯-甲基丙烯酸正癸酯-甲基丙烯酸异冰片酯（MMA-DMA-IBMA）骨水泥（Boneloc（R ）），同时降低了聚合热和单体渗漏，另外六只狗的一只胫骨装有MMA-DMA-IBMA，对侧胫骨装有骨蜡。用微球技术测量，充满MMA-DMA-IBMA的腿比充满PMMA的腿的骨干血流量更高。蜡填充的骨骼比MMA-DMA-IBMA骨骼的血液灌注更高。我们发现更高的（99m）label标记的二膦酸二甲酯（（99m）TcMDp）摄取趋势，放射自显影显示在骨膜下并存处和皮层中，充满新骨的骨骼有较大的骨膜下并发和更黑的趋势。骨水泥在第一个系列中，但在蜡填充的骨头中在第二个系列中。结论是，与标准的丙烯酸骨水泥相比，新的骨水泥似乎抑制血管反应和骨重塑活性的降低，从而使更早的重塑成为可能。但是，与骨蜡相比，新的骨水泥似乎仍能抑制骨血灌注。 [参考：17]

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