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首页> 外文期刊>Seminars in Respiratory and Critical Care Medicine >Clinical stability versus clinical failure in patients with community-acquired pneumonia
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Clinical stability versus clinical failure in patients with community-acquired pneumonia

机译：社区获得性肺炎患者的临床稳定性与临床失败

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Once antibiotics have been started in patients with community-acquired pneumonia (CAP), the evaluation of clinical outcomes represents one of the essential steps in patient care. Among CAP patients who improve, recognition of clinical stability should be based on both subjective and objective parameters that are locally available in the everyday clinical practice. Different steps in the management of the pneumonia depend on this early outcome, including the switch from intravenous to oral antibiotics, patients' discharge from the hospital, and outcomes after hospitalization. When deterioration occurs in CAP patients, a "treatment failureo" or a "clinical failureo" should be identified. It is crucial to understand the etiology of failure so as to develop different measures at both international and local levels to prevent adverse outcomes. Finally, several efforts should be made to define incidence, timing, and risk factors for nonresolving pneumonia that, to date, remains one of the most indeterminate clinical outcomes in patients with CAP.
机译：一旦社区获得性肺炎（CAP）患者开始使用抗生素，对临床结局的评估就代表了患者护理中必不可少的步骤之一。在改善的CAP患者中，对临床稳定性的认识应基于日常临床实践中局部可用的主观和客观参数。肺炎治疗的不同步骤取决于这种早期结果，包括从静脉使用抗生素改为口服抗生素，患者出院以及住院后的结果。当CAP患者发生恶化时，应确定“治疗失败”或“临床失败”。了解失败的病因至关重要，以便在国际和地方各级制定不同的措施以防止不良后果。最后，应该做出一些努力来确定非解决性肺炎的发生率，时机和风险因素，迄今为止，这些因素仍然是CAP患者最不确定的临床结局之一。

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