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首页> 外文期刊>Biomaterials >Titanium metals form direct bonding to bone after alkali and heat treatments.
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Titanium metals form direct bonding to bone after alkali and heat treatments.

机译：钛金属经过碱和热处理后形成与骨骼的直接键合。

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摘要

In this article we evaluated the bone-bonding strengths of titanium and titanium alloy implants with and without alkali and heat treatments using the conventional canine femur push-out model. Four kinds of smooth cylindrical implants, made of pure titanium or three titanium alloys, were prepared with and without alkali and heat treatments. The implants were inserted hemitranscortically into canine femora. The bone-bonding shear strengths of the implants were measured using push-out test. At 4 weeks all types of the alkali- and heat-treated implants showed significantly higher bonding strength (2.4-4.5 MPa) than their untreated counterparts (0.3-0.6 MPa). At 12 weeks the bonding strengths of the treated implants showed no further increase, while those of the untreated implants had increased to 0.6-1.2MPa. Histologically, alkali- and heat-treated implants showed direct bonding to bony tissue without intervening fibrous tissue. On the other hand, untreated implants usually had intervening fibrous tissue at the interface between bone and the implant. The early and strong bonding to bone of alkali- and heat-treated titanium and its alloys without intervening fibrous tissue may be useful in establishing cementless stable fixation of orthopedic implants.
机译：在本文中，我们使用常规犬股骨推出模型评估了有无碱和热处理的钛和钛合金植入物的骨结合强度。制备了四种由纯钛或三种钛合金制成的光滑圆柱状植入物，这些植入物经过或不经过碱和热处理。将植入物半皮皮质地插入犬股骨中。使用推出试验测量植入物的骨结合剪切强度。在第4周，所有类型的经过碱和热处理的植入物均显示出比未处理的植入物（0.3-0.6 MPa）更高的结合强度（2.4-4.5 MPa）。在12周时，经处理的植入物的粘结强度没有进一步增加，而未经处理的植入物的粘结强度已经增加至0.6-1.2MPa。从组织学上讲，经碱和热处理的植入物表现出与骨组织的直接结合，而没有介入纤维组织。另一方面，未经处理的植入物通常在骨骼和植入物之间的界面处具有介入的纤维组织。在不干预纤维组织的情况下，将经过碱和热处理的钛及其合金与骨骼的早期牢固结合可能对建立整形外科植入物的非骨水泥稳定固定很有用。

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