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首页> 外文期刊>Spine >Postoperative culture positive surgical site infections after the use of irradiated allograft, nonirradiated allograft, or autograft for spinal fusion.
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Postoperative culture positive surgical site infections after the use of irradiated allograft, nonirradiated allograft, or autograft for spinal fusion.

机译：使用辐照的同种异体移植物，非辐照的同种异体移植物或自体移植物进行脊柱融合后的术后培养阳性手术部位感染。

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STUDY DESIGN: Retrospective chart review. OBJECTIVE: We report the rate of postoperative infection at our institution following the use of irradiated allograft, nonirradiated allograft, or autograft for spinal fusion procedures. SUMMARY OF BACKGROUND DATA: Infection after a spinal fusion procedure is a devastating complication. It has not been defined whether spine bone graft preparation has any correlation with postoperative infection in spinal fusion procedures. METHODS: We retrospectively identified 1435 patients who underwent spine fusion procedures with a minimum 1-year follow-up. Irradiated allograft was used in 144 patients, nonirradiated allograft was used in 441 patients, and autograft was used in 850 patients. Postoperative spinal infection was based on documented positive spine cultures at the time of re-exploration for presumed infection. Infection rates were estimated using the method of Kaplan and Meier; estimates were calculated out to 1-year postsurgery, and rates were compared using log-rank tests. RESULTS: No significant difference in the rate of surgical site infection at 1 year was observed after the use of irradiated allograft (1.7%), nonirradiated allograft (3.2%), or autograft (4.3%), P = 0.51. CONCLUSION: There is no significant difference in the rate of infection following spine fusion using irradiated allograft, nonirradiated allograft, or autograft. The selection of bone graft to aid in spinal fusion should be based on the requirements of surgical technique and availability of the desired tissue and not on a perceived association with postoperative infection.
机译：研究设计：回顾性图表审查。目的：我们报告了在使用辐照的同种异体移植物，未辐照的同种异体移植物或自体移植物进行脊柱融合手术后，我们机构的术后感染率。背景数据摘要：脊柱融合手术后的感染是毁灭性的并发症。在脊柱融合手术中，脊柱骨移植物的制备与术后感染是否相关，目前尚无定论。方法：我们回顾性鉴定了1435例接受脊柱融合手术并至少随访1年的患者。 144例使用了同种异体移植，441例使用了非同种异体移植，850例使用了自体异体移植。术后脊柱感染的依据是在重新探究推定的感染时所记录的阳性脊柱培养物。感染率使用Kaplan和Meier方法估算;计算出术后1年的估计值，并使用对数秩检验比较比率。结果：使用辐照的同种异体移植物（1.7％），未辐照的同种异体移植物（3.2％）或自体移植物（4.3％）后1年，手术部位感染率没有显着差异，P = 0.51。结论：采用辐照同种异体移植，非辐照同种异体移植或自体移植的脊柱融合术后感染率没有显着差异。选择骨移植以帮助脊柱融合应基于手术技术的要求和所需组织的可用性，而不是基于与术后感染的关联。

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