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首页> 外文期刊>Spine >Effects of endplate removal on the structural properties of the lower lumbar vertebral bodies.
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Effects of endplate removal on the structural properties of the lower lumbar vertebral bodies.

机译：终板移除对下腰椎椎体结构特性的影响。

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摘要

STUDY DESIGN: A biomechanical investigation using indentation tests in human cadaveric lumbar vertebrae. OBJECTIVES: To determine the effect of endplate removal on the structural properties across the lower lumbar vertebral bodies (L3-L5). SUMMARY OF BACKGROUND DATA: The structural properties of the vertebral endplates exhibit substantial regional variation. In addition, several recent studies of the endplate-implant interface have suggested that the endplate is not a significant structural element. METHODS: The bony endplates on the left or right side of seven intact human vertebrae (L3-L5) were removed with a high-speed burr. Indentation tests were performed at standardized test sites on both sides of the endplate using a 3-mm diameter, hemispherical indenter with a test rate of 0.2 mm/s to a depth of 3 mm. The failure load and stiffness at each site were determined from the load-displacement curves. Three-way repeated measures analyses of variance were used to analyze the resulting data for variation in the anterior-posterior and lateral directions, as well as to determine the effect of endplate removal. RESULTS: For the intact endplates, both the failure load and stiffness varied significantly across the endplate surfaces (P < 0.0001), with the posterolateral regions being stronger and stiffer than the central regions. With endplate removal, the mean failure load decreased to about 33% of the intact failure load, a significant drop (P = 0.04), and there was a trend toward greater decreases posteriorly (P = 0.05). With endplate removal, the mean stiffness also decreased significantly (P = 0.01), with the greater decreases occurring laterally (P = 0.04). CONCLUSIONS: There was a significant effect of endplate removal on the local structural characteristics of the vertebral endplate.
机译：研究设计：使用压痕测试对人体尸体腰椎进行生物力学研究。目的：确定端板拆除对下腰椎椎体（L3-L5）的结构特性的影响。背景数据摘要：椎骨终板的结构特性表现出明显的区域差异。此外，最近对端板-植入物界面的研究表明，端板不是重要的结构元件。方法：用高速毛刺去除七个完整人类椎骨（L3-L5）左侧或右侧的骨质终板。压痕测试是在端板两侧的标准测试点上使用直径3mm的半球形压头以0.2mm / s的测试速率进行3mm深度的压痕测试。根据载荷-位移曲线确定每个部位的破坏载荷和刚度。使用三向重复测量方差分析来分析所得数据的前后和横向变化，并确定端板移除的效果。结果：对于完整的终板，破坏载荷和刚度在终板表面上均发生显着变化（P <0.0001），后外侧区域比中央区域更坚固。移开端板后，平均破坏载荷下降到完整破坏载荷的33％左右，显着下降（P = 0.04），并且有向后减小的趋势（P = 0.05）。移除终板后，平均刚度也显着下降（P = 0.01），而横向刚度的下降幅度更大（P = 0.04）。结论：终板去除对椎骨终板的局部结构特征有显着影响。

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