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首页> 外文期刊>Spine >The leakage pathway and effect of needle gauge on degree of disc injury post anular puncture: a comparative study using aged human and adolescent porcine discs.
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The leakage pathway and effect of needle gauge on degree of disc injury post anular puncture: a comparative study using aged human and adolescent porcine discs.

机译：肛门穿刺后椎间盘损伤程度的泄漏途径和针规的影响：使用老年人和青少年猪椎间盘的比较研究。

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摘要

STUDY DESIGN: An in vitro biomechanical study using aged human and adolescent porcine discs. OBJECTIVES: To find the leakage pathway and effect of needle gauge on the degree of disc injury post anular puncture. SUMMARY OF BACKGROUND DATA: Spinal needles are widely used for minimal invasive disc surgeries and disc degeneration/regeneration research. Applications of anular puncture require different diameters of spinal needles. However, the effect of needle diameters on the disc injury has not been systematically studied yet. METHODS: Four groups of experiments were conducted: 1) porcine thoracic disc, 2) human thoracic disc, 3) porcine thoracic disc with 200 N external loading, and 4) porcine lumbar discs. The disc was punctured consecutively with needles from smaller diameter to larger diameter. After each anular puncture, the quantitative discomanometry technique was conducted to quantify the disc rupture pressure and volume. The association between needle gauge and rupture pressure and volume was analyzed. RESULTS: The degree of disc injury increased with the diameter of needle. For an aged human thoracic disc, the anulus fibrosus cannot hold pressure more than 2 MPa after a 21-gauge-needle-anular-puncture. The leakage pathway of injected saline was through the anular fissure but was through the endplate when the disc was next to an osteoporotic vertebrae. The pressure holding power of porcine disc is stronger than of human disc. The rupture pressure of porcine lumbar disc is higher than of porcine thoracic disc. The axial compressive external loading increased the disc rupture pressure. The rupture volumes were not affected by the dimension of injury fissure. The rupture volume was at level of 0.3 mL without external loading and at 0.2 mL with external loading. CONCLUSION: A spinal needle of < or 22 gauge and injection volume of < or postsurgery leakage.
机译：研究设计：使用老年人和青少年猪圆盘的体外生物力学研究。目的：探讨针刺穿刺术后椎间盘损伤程度的渗漏途径和针刺规的影响。背景技术摘要：脊柱针被广泛用于微创椎间盘手术和椎间盘退变/再生研究。肛门穿刺的应用需要不同直径的脊髓针。但是，针头直径对椎间盘损伤的影响尚未得到系统的研究。方法：进行了四组实验：1）猪胸椎盘，2）人胸椎盘，3）外部负荷为200 N的猪胸椎盘和4）猪腰椎盘。用从小直径到大直径的针连续刺穿椎间盘。每次肛门穿刺后，采用定量容积比术技术定量椎间盘破裂压力和体积。分析了针规与破裂压力和体积之间的关系。结果：椎间盘损伤程度随针头直径的增加而增加。对于老年人的胸椎盘，在针规21针的情况下，纤维环的压力不能超过2 MPa。当椎间盘靠近骨质疏松椎骨时，注入的盐水的泄漏途径是通过肛裂，但是通过终板。猪椎间盘的压力保持能力强于人椎间盘。猪腰椎间盘的破裂压力高于猪胸椎间盘的破裂压力。轴向压缩外部载荷增加了椎间盘破裂压力。破裂体积不受损伤裂缝尺寸的影响。无外部载荷时的破裂体积为0.3 mL，有外部载荷时的破裂体积为0.2 mL。结论：<或22号规格的脊柱针和<或术后泄漏的注射量。

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