The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice

Shimomatsu Tatsuya; Kanazawa Nobuo; Mikita Naoya; Nakatani Yumi; Li Hong-jin; Inaba Yutaka; Ikeda Takaharu; Kondo Toshikazu; Furukawa Fukumi

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The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice

机译：羟氯喹对MRL / lpr小鼠红斑狼疮样皮肤损伤的影响

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Objectives: To evaluate the effect and safety of hydroxychloroquine (HCQ) on lupus erythematosus (LE)-like skin lesions in the MRL/lpr mouse, a model for systemic LE (SLE).

机译：目的：评估羟氯喹（HCQ）对MRL / lpr小鼠（系统性LE（SLE）的模型）红斑狼疮（LE）样皮肤损伤的作用和安全性。

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来源
《Modern rheumatology》 |2016年第5期|共5页
作者
Shimomatsu Tatsuya; Kanazawa Nobuo; Mikita Naoya; Nakatani Yumi; Li Hong-jin; Inaba Yutaka; Ikeda Takaharu; Kondo Toshikazu; Furukawa Fukumi;
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正文语种 eng
中图分类免疫性疾病;
关键词
Hydroxychloroquine; Mast Cell; MRL/Lpr mice; Skin lesion; Systemic lupus erythematosus;

机译：羟氯喹;肥大细胞;MRL / Lpr小鼠;皮肤病变;系统性红斑狼疮;

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专利

1. The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice [J] . Shimomatsu Tatsuya, Kanazawa Nobuo, Mikita Naoya, Modern rheumatology . 2016,第5期

机译：羟氯喹对MRL / lpr小鼠红斑狼疮样皮肤损伤的影响
2. Severer lupus erythematosus-like skin lesions in MRL/lpr mice with homozygous Kit(wsh/wsh) mutation [J] . Inaba Yutaka, Kanazawa Nobuo, Yoshimasu Takashi, Modern rheumatology . 2018,第2期

机译：SELERER LUPUS红斑狼疮样MRL / LPR小鼠的皮肤病变与纯合套件（WSH / WSH）突变
3. The Protective Effects of Ultraviolet A1 Irradiation on Spontaneous Lupus Erythematosus-Like Skin Lesions in MRL/lpr Mice [J] . NaoyaMikita, NobuoKanazawa, TakashiYoshimasu, Developmental Immunology: Journal of Immunology Research . 2009,第2期

机译：紫外线A1对MRL / lpr小鼠自发性红斑狼疮样皮肤病变的保护作用
4. The therapeutic effect and mechanism of human bone marrow mesenchymal stem cells transplantation in MRL/lpr mice [C] . Kang-Xing Zhou, Ou-Yang Jin, Xue-Bing Feng, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：人骨髓间充质干细胞移植对MRL / lpr小鼠的治疗作用及机制
5. Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment. [D] . Kim, Caius. 1991

机译：通过细菌超抗原治疗减少MRL / lpr小鼠中的狼疮肾炎。
6. The Protective Effects of Ultraviolet A1 Irradiation on Spontaneous Lupus Erythematosus-Like Skin Lesions in MRL/lpr Mice [O] . Naoya Mikita, Nobuo Kanazawa, Takashi Yoshimasu, 2009

机译：紫外线A1对MRL / lpr小鼠自发性红斑狼疮样皮肤病变的保护作用
7. The Protective Effects of Ultraviolet A1 Irradiation on Spontaneous Lupus Erythematosus-Like Skin Lesions in MRL/lpr Mice [O] . Mikita, Naoya, Kanazawa, Nobuo, Yoshimasu, Takashi, 2009

机译：紫外线A1对MRL / lpr小鼠自发性红斑狼疮样皮肤病变的保护作用

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice

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