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首页> 外文期刊>Modern rheumatology >Induction of clinical remission with adalimumab-methotrexate combination therapy in a patient with rheumatoid arthritis and concomitant hepatitis C virus infection
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Induction of clinical remission with adalimumab-methotrexate combination therapy in a patient with rheumatoid arthritis and concomitant hepatitis C virus infection

机译：类风湿关节炎并发丙型肝炎病毒感染的患者使用阿达木单抗-甲氨蝶呤联合治疗可诱导临床缓解

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摘要

The patient described here is a 49-year-old woman who had hepatitis C virus (HCV) infection and rheumatoid arthritis (RA). Her RA had been successfully managed with methotrexate for about 10 years. After a sustained virological response was achieved with interferon therapy, treatment with adalimumab was instituted. This resulted in a rapid and sustained remission that lasted for more than a year, without HCV reactivation. The results in this case suggest that a sequential strategy, with initial HCV clearance followed by the targeting of remission with biologics, may be a favorable option in patients with RA and concomitant HCV infection.
机译：此处描述的患者是一名49岁的女性，患有丙型肝炎病毒（HCV）感染和类风湿关节炎（RA）。她的RA已成功接受甲氨蝶呤治疗约10年。干扰素治疗达到持续的病毒学应答后，开始使用阿达木单抗治疗。这导致持续持续超过一年的快速且持续的缓解，而HCV没有重新激活。在这种情况下的结果表明，先发性HCV清除然后以生物制剂缓解的靶向治疗的循序治疗策略可能是RA和伴随HCV感染患者的理想选择。

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