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首页> 外文期刊>Modern rheumatology >One third of Japanese patients with rheumatoid arthritis use complementary and alternative medicine.
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One third of Japanese patients with rheumatoid arthritis use complementary and alternative medicine.

机译：日本患有类风湿关节炎的患者中有三分之一使用补充和替代药物。

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摘要

We investigated the prevalence and predictors of complementary and alternative medicine (CAM) use by patients with rheumatoid arthritis (RA) in Japan. A cross-sectional descriptive study was performed using the database from a large observational cohort of RA patients in the Institute of Rheumatology, Tokyo Women's Medical University. Logistic regression analysis was carried out to reveal predictive factors for CAM use. Among 3815 RA patients, 1321 (34.6%; 174 males, 1147 females) used at least one type of CAM. Health foods, including dietary supplements, were the most commonly used. CAM was more frequently used by female patients (odds ratio: 0.578; 95% confidence interval [CI] = 0.451-0.740). A multiple logistic regression analysis revealed that sex (odds ratio: 0.489; 95% CI 0.333-0.718) and degree of satisfaction with disease-modifying antirheumatic drugs (DMARDs) (odds ratio: 0.899; 95% CI = 0.852-0.948) were significant independent predictive factors for CAM use. The serum C-reactive protein level and erythrocyte sedimentation rate showed no significant associations with CAM use. Approximately 35% of RA patients used CAM in Japan. Female patients and patients dissatisfied with DMARDs used CAM more frequently, regardless of their disease activity.
机译：我们调查了日本类风湿关节炎（RA）患者使用补充和替代药物（CAM）的普遍性和预测因素。使用来自东京女子医科大学风湿病研究所的大量RA患者的观察队列的数据库进行了横断面描述性研究。进行逻辑回归分析以揭示CAM使用的预测因素。在3815名RA患者中，有1321名（34.6％;男174名，女1147名）使用了至少一种CAM。最常用的保健食品包括膳食补充剂。女性患者更常使用CAM（赔率：0.578; 95％置信区间[CI] = 0.451-0.740）。多元logistic回归分析显示，性别（比值比：0.489; 95％CI 0.333-0.718）和对疾病改变性抗风湿药（DMARDs）的满意度（比值比：0.899; 95％CI = 0.852-0.948）很显着CAM使用的独立预测因素。血清C反应蛋白水平和红细胞沉降率与CAM的使用无显着相关性。在日本，大约35％的RA患者使用了CAM。女性患者和对DMARDs不满意的患者更经常使用CAM，无论其疾病活动如何。

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