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首页> 外文期刊>Modern rheumatology >Quality of life evaluated by Short Form-8 in patients with rheumatoid arthritis who were receiving infusion of infliximab.
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Quality of life evaluated by Short Form-8 in patients with rheumatoid arthritis who were receiving infusion of infliximab.

机译：接受英夫利昔单抗输注的类风湿关节炎患者通过Short Form-8评估生活质量。

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摘要

In this study, influences of infliximab to health-related quality of life (HRQOL) and active status of RA were assessed. Between 2003 and 2006, 22 patients with rheumatoid arthritis (RA) began receiving infusion of infliximab. Of all the patients, 17 patients who were followed for at least 30 weeks (102 weeks at maximum) after the start of infliximab were included in this study. The mean age was 54.6 +/- 10 years. HRQOL was evaluated with use of the SF-8trade mark, which is a simple version of the Medical Outcome Study Short Form 36. As an index of active status of RA, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and rheumatoid factor (RF) were collected. CRP and ESR significantly improved at the final follow-up, but RF did not. All subscales of the SF-8 were significantly improved after the start of infliximab. However, there were three patients whose laboratory data were improved, but HRQOL was not. We should not be prepossessed only with laboratory data in treating patients with RA. We recommend that the SF-8 to evaluate HRQOL of patients with RA in busy outpatient clinics because it is both simple and convenient.
机译：在这项研究中，评估了英夫利昔单抗对健康相关生活质量（HRQOL）和RA活跃状态的影响。在2003年至2006年之间，有22名类风湿关节炎（RA）患者开始接受英夫利昔单抗的输注。在所有患者中，英夫利昔单抗开始后至少随访30周（最多102周）的17位患者被纳入本研究。平均年龄为54.6 +/- 10岁。 HRQOL使用SF-8商标进行了评估，该商标是医学成果研究简写36的简单版本。作为RA活跃状态的指标，C反应蛋白（CRP），红细胞沉降率（ESR），并收集类风湿因子（RF）。在最后的随访中，CRP和ESR明显改善，但RF没有改善。英夫利昔单抗开始后，SF-8的所有分量表均得到明显改善。但是，有3例患者的实验室数据有所改善，而HRQOL却没有。我们不应仅凭实验室数据来治疗RA患者。我们建议使用SF-8来评估门诊繁忙的RA患者的HRQOL，因为它既简单又方便。

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