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首页> 外文期刊>Stem cell reviews >Cord-blood mesenchymal stem cells and tissue engineering.
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Cord-blood mesenchymal stem cells and tissue engineering.

机译:脐血间充质干细胞和组织工程。

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Institute of Reconstructive Plastic Surgery, Laboratory of Vascular Tissue Engineering and Microvascular Research, New York University, New York, NY and Long Island Plastic Surgical Group, Garden City, NY Cord-blood-derived stem cells have proven clinically useful for numerous disease states, as have mesenchymal stem cells (MSCs) derived from bone marrow and adipose tissue. The recent identification of MSCs in cord-blood heralds cord-blood as an untapped resource for nonhematopoietic stem cell-based therapeutic strategies for the replacement of injured or diseased connective tissue. This review discusses the potential for tissue engineering applications of MSCs, highlighting the development of vascularized tissue engineering constructs using microvascular free flaps as a novel tissue engineering strategy.
机译:纽约大学,纽约大学重建组织整形外科研究所,血管组织工程和微血管研究实验室,纽约州加登市的长岛整形外科小组,已证明脐带血干细胞在临床上可用于多种疾病,源自骨髓和脂肪组织的间充质干细胞(MSC)也是如此。脐带血中的MSCs的最新鉴定表明,脐带血是非造血干细胞疗法替代受伤或患病结缔组织的未开发资源。这篇综述讨论了MSCs在组织工程中的应用潜力,强调了使用无微血管皮瓣作为一种新颖的组织工程策略的血管化组织工程结构的发展。

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