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首页> 外文期刊>Stroke: A Journal of Cerebral Circulation >Factors associated with a high risk of recurrence in patients with transient ischemic attack or minor stroke.
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Factors associated with a high risk of recurrence in patients with transient ischemic attack or minor stroke.

机译：与短暂性脑缺血发作或轻度中风患者高复发风险相关的因素。

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BACKGROUND AND PURPOSE: The aim of our study was to identify factors associated with stroke recurrence after an initial minor stroke or transient ischemic attack (TIA) in a prospective hospital-series. METHODS: Included in the series were 689 patients with NIHSS lower than 4 at hospital admission. The end point was a new neurological event (worsening >/=4 points in the initial NIHSS was considered as recurrence) at 90 days (and additionally at 7 days). Factors based on two previous reported scores (ABCD and SPI-II) were analyzed in relation with stroke recurrence: age, duration of symptoms >1 hour, weakness, speech impairment, initial hypertension, hypertension, diabetes, coronary disease, minor stroke versus TIA, prior stroke, and heart failure. We also analyzed: gender, hyperlipidemia, severe alcohol intake (>60gr/d), current smoking habits, peripheral arterial disease, atrial fibrillation, acute lesion in initial head computed tomography, severe symptomatic extra or intracranial arterial disease (SSAD; arterial stenosis >/=70%), previous TIA, and vertebrobasilar event. Patients were also analyzed separately according to diagnosis of TIA or minor stroke. RESULTS: 90-day recurrence occurred in 111 patients (16.1%), whereas 62 patients had 7-day recurrence (9%). The independent variables associated with 90-day recurrence were: SSAD (OR=4.97), weakness (OR=3.25), speech impairment (OR=1.96), severe alcohol intake (OR=4.18), heart failure (OR=2.41), previous TIA (OR=4.62), and vertebrobasilar events (OR=2.87). SSAD was independently associated with 7-day recurrence (OR=7.73) and also for TIA (OR=3.45) and minor stroke (OR=5.15) patients. CONCLUSIONS: An arterial study to discard SSAD would be necessary, in combination with clinical factors, to improve the identification of patients with a higher risk of 90-day recurrence after an initial minor stroke or TIA.
机译：背景与目的：我们的研究目的是在预期的医院系列中确定与最初的轻度中风或短暂性脑缺血发作（TIA）后中风复发相关的因素。方法：该系列包括689例入院时NIHSS低于4的患者。终点是在90天时（另外在7天时）发生的新的神经系统事件（初始NIHSS中恶化> / = 4点被视为复发）。分析了基于先前报告的两个得分（ABCD和SPI-II）的因素与中风复发的关系：年龄，症状持续时间大于1小时，虚弱，语言障碍，初始高血压，高血压，糖尿病，糖尿病，冠心病，轻度卒中与TIA ，先前的中风和心力衰竭。我们还分析了：性别，高脂血症，严重饮酒（> 60gr / d），当前吸烟习惯，周围动脉疾病，房颤，最初的头部计算机断层扫描中的急性病变，严重的有症状的颅外或颅内动脉疾病（SSAD;动脉狭窄> / = 70％），先前的TIA和椎基底动脉事件。还根据TIA或轻度中风的诊断对患者进行了单独分析。结果：111例患者发生90天复发（16.1％），而7例患者发生7天复发（9％）。与90天复发相关的独立变量为：SSAD（OR = 4.97），无力（OR = 3.25），语言障碍（OR = 1.96），严重饮酒（OR = 4.18），心力衰竭（OR = 2.41），之前的TIA（OR = 4.62）和椎基底基底膜事件（OR = 2.87）。 SSAD与7天复发（OR = 7.73）以及TIA（OR = 3.45）和轻度中风（OR = 5.15）患者独立相关。结论：有必要结合临床因素进行一项动脉研究以丢弃SSAD，以改善对初次中风或TIA后90天复发风险较高的患者的识别。

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