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首页> 外文期刊>Chemical Society Reviews >Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications
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Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications

机译：利用离子浓度极化的生物分子纳米流体浓缩装置：理论，制造和应用

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摘要

Recently, a new type of electrokinetic concentration devices has been developed in a microfluidic chip format, which allows efficient trapping and concentration of biomolecules by utilizing ion concentration polarization near nanofluidic structures. These devices have drawn much attention not only due to their potential application in biomolecule sensing, but also due to the rich scientific content related to ion concentration polarization, the underlying physical phenomenon for the operation of these electrokinetic concentration devices. This tutorial review provides an introduction to the scientific and engineering advances achieved, in-depth discussion about several interesting applications of these unique concentration devices, and their current limitations and challenges.
机译：最近，以微流控芯片形式开发了一种新型的电动浓缩设备，该设备可以通过利用纳米流体结构附近的离子浓差极化有效地捕获和浓缩生物分子。这些设备不仅因为它们在生物分子传感中的潜在应用，而且由于与离子浓度极化有关的丰富的科学内容而受到关注，这些离子浓度极化是这些电动浓度设备运行的潜在物理现象。本教程概述提供了对科学和工程技术进步的介绍，对这些独特的浓缩装置的几种有趣应用及其当前的局限性和挑战进行了深入的讨论。

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