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Comparison of serum C-reactive protein concentrations for laparoscopic versus open cholecystectomy.

机译：腹腔镜与开腹胆囊切除术的血清C反应蛋白浓度比较

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摘要

In an attempt to quantify the difference in tissue damage between open cholecystectomy (OC) and laparoscopic cholecystectomy (LC), we have compared in a prospective manner the pre- and post-operative concentrations of serum C-reactive protein (CRP) in 17 patients undergoing LC and 13 patients undergoing OC. In addition, we measured the pre- and postoperative white blood cell counts (WBC), the postoperative body temperature, and the postoperative duration of hospitalization. There were no differences in the preoperative serum CRP concentrations--5.9 +/- 2.62 mg/l (mean +/- SD) for the LC group and 6.12 +/- 2.38 mg/l for the OC group. Serum CRP rose markedly following OC compared to that of patients who underwent LC (128.6 +/- 45.1 mg/l vs 26.8 +/- 10.5 mg/l) (P < 0.001). There were also significant differences in the postoperative WBC count (14,000 +/- 2,900 cells for the OC group vs 10,600 +/- 3,000 cells for the LC group), the postoperative body temperature (37.5 +/- 0.3 degrees C vs 37.0 +/- 0.3 degrees C), and the postoperative hospital stay (5.5 +/- 1.5 days vs 1.9 +/- 0.9 days). There was no correlation between serum CRP concentrations and the other postoperative parameters. These results provide us with biochemical evidence supporting the clinical observation that LC is far less traumatic to the patient than OC.
机译：为了量化开腹胆囊切除术（OC）和腹腔镜胆囊切除术（LC）之间组织损伤的差异，我们以前瞻性的方式比较了17例患者术前和术后的血清C反应蛋白浓度接受LC和13例接受OC的患者。此外，我们测量了术前和术后白细胞计数（WBC），术后体温和住院时间。术前血清CRP浓度无差异-LC组为5.9 +/- 2.62 mg / l（平均+/- SD），而OC组为6.12 +/- 2.38 mg / l。与接受LC的患者相比，OC后的血清CRP明显升高（128.6 +/- 45.1 mg / l与26.8 +/- 10.5 mg / l）（P <0.001）。术后白细胞计数（OC组为14,000 +/- 2,900个细胞，LC组为10,600 +/- 3,000个细胞），术后体温（37.5 +/- 0.3摄氏度和37.0 + / -0.3摄氏度），以及术后住院时间（5.5 +/- 1.5天与1.9 +/- 0.9天）。血清CRP浓度与其他术后参数之间没有相关性。这些结果为我们提供了支持临床观察的生化证据，即LC对患者的伤害远小于OC。

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