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Randomized controlled trial comparing three methods of liver retraction in laparoscopic Roux-en-Y gastric bypass

机译:随机对照试验比较腹腔镜Roux-en-Y胃旁路术中三种肝退缩方法

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Background: This study aimed to evaluate differences between three methods of liver retraction during laparoscopic Roux-en-Y Gastric bypass (LRYGB) and to compare novel liver retraction techniques with the traditional mechanical liver retractor in a randomized controlled trial. Methods: In this study, 60 obese patients (26 males and 34 females) who underwent LRYGB between January and July 2010 were randomized to one of three groups (20 in each): group 1 (Nathanson liver retractor), group 2 (liver suspension tape), and group 3 (V-shaped liver suspension technique [V-LIST]). Data regarding demographics (age, sex, body mass index); liver function test (LFT) just before surgery; postoperative results immediately, then 18 h, 1 week, and 1 month after surgery; operative data, and visual analog scale (VAS) for pain on postoperative days (PODs) 1 and 2 were calculated and analyzed. Results: The groups did not differ significantly in terms of preoperative LFT or operative data except that group 3 took significantly longer time for liver suspension than group 1 (p = 0.01) or group 2 (p = 0.03). The VAS score in group 2 was significantly lower on POD 1 than in group 1 (p = 0.04). Group 1 showed a significant rise in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) at 18 h compared with group 2 (p < 0.01 and p = 0.02, respectively) and group 3 (p < 0.01 and p = 0.01), at 1 week compared with group 2 (p = 0.04 and 0.04), and in AST levels alone during the immediate postoperative compared with group 3 (p = 0.04). Conclusion: The Nathanson liver retractor causes more liver dysfunction than V-LIST or the liver suspension technique and causes more postoperative pain than the liver suspension technique. Both V-LIST and liver suspension tape have a short learning curve and implications for single-port surgery.
机译:背景:本研究旨在评估腹腔镜Roux-en-Y胃旁路术(LRYGB)期间三种肝收缩方法之间的差异,并在一项随机对照试验中比较新型肝收缩技术与传统机械肝收缩器。方法:在本研究中,将60名在2010年1月至2010年7月间接受LRYGB治疗的肥胖患者(男26例,女34例)随机分为三组(每组20例)之一:第1组(Nathanson肝牵开器),第2组(肝悬吊)胶带)和第3组(V形肝悬液技术[V-LIST])。有关人口统计数据(年龄,性别,体重指数);手术前的肝功能检查(LFT);手术后18小时,1周和1个月立即获得术后结果;计算并分析手术数据以及术后1天和2天的疼痛视觉模拟量表(VAS)。结果:各组在术前LFT或手术数据方面无显着差异,只是第3组的肝悬浮时间比第1组(p = 0.01)或第2组(p = 0.03)长得多。第2组的VAS评分在POD 1上显着低于第1组(p = 0.04)。与第2组(分别为p <0.01和p = 0.02)和第3组(p <0.01和p = 0.01)相比,第1组在18 h时天门冬氨酸转氨酶(AST)和丙氨酸转氨酶(ALT)显着升高。与第2组相比分别为1周(p = 0.04和0.04),而在术后即刻与单独使用AST水平相比,与第3组相比(p = 0.04)。结论:Nathanson肝牵开器比V-LIST或肝悬挂技术引起的肝功能障碍更多,并且比肝悬挂技术引起的术后疼痛更大。 V-LIST和肝悬吊带都具有较短的学习曲线,对单端口手术具有重要意义。

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