...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Evaluation of bacterial contamination after 'pure' (totally) transvaginal NOTES? diagnostic peritoneoscopy with biopsies in swine: A comparative study with laparoscopy
【24h】

Evaluation of bacterial contamination after 'pure' (totally) transvaginal NOTES? diagnostic peritoneoscopy with biopsies in swine: A comparative study with laparoscopy

机译：评估“纯”（全部）经阴道后的细菌污染NOTES？猪活检的诊断性腹膜镜：腹腔镜的比较研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: Bacterial contamination from viscerotomy is a barrier to natural orifice translumenal endoscopic surgery (NOTES). The aim of this survival study is to evaluate pure (totally) transvaginal NOTES bacterial contamination compared with laparoscopy in pigs. Methods: Twelve adult female pigs underwent peritoneoscopy with liver and peritoneal biopsies, using either laparoscopy (Glap, six animals) or pure transvaginal (GNOTES) access, and were maintained alive for 7 days. In all animals, blood cultures were taken at baseline, and after 24 h and 7 days postoperatively. Swab cultures from vagina (GNOTES) and skin (Glap) were obtained pre- and post-antisepsis. Peritoneal fluid culture was obtained at necropsy. For statistical analysis, Glap and GNOTES were compared for presence of positive bacterial cultures (qualitative bacterial analysis) using Fisher's test, with level of significance set at p < 0.05. Results: All animals had good postoperative outcome. One animal had transient perioperative bleeding from a transvaginal access. Two animals in Glap and one in GNOTES had positive blood cultures after the procedure. All animals from GNOTES and Glap presented with mixed flora pre-antisepsis. After antisepsis, one animal (GNOTES) presented with a positive vaginal swab culture (a single bacterial strain was identified). There was no positive skin swab culture in Glap. There were no signs of intra-abdominal infection at necropsy. In two animals, one from Glap and another from GNOTES, intra-abdominal culture was positive for Corynebacterium spp. and Escherichia coli, respectively. There was no correlation between the bacterial flora found at the access site and in the peritoneal cultures. Conclusions: Pure transvaginal peritoneoscopy with liver and peritoneal biopsy in swine is feasible and associated with bacterial contamination comparable to laparoscopy. Peritoneal bacterial contamination was clinically insignificant after 1 week postoperatively. Preoperative antisepsis provided significant reduction of bacterial load prior to transvaginal and laparoscopic procedures.
机译：简介：内脏切开术对细菌的污染是自然孔腔内腔镜手术（NOTES）的障碍。这项生存研究的目的是评估与猪腹腔镜检查相比纯的（全部）经阴道NOTES细菌污染。方法：对十二只成年雌性猪进行腹腔镜肝和腹膜活检，使用腹腔镜检查（Glap，六只动物）或纯经阴道检查（GNOTES），并存活7天。在所有动物中，在基线时以及术后24小时和7天后进行血液培养。在前和后分别获得来自阴道（GNOTES）和皮肤（Glap）的拭子培养物。尸检时进行腹膜液培养。为了进行统计分析，使用Fisher检验比较了Glap和GNOTES阳性细菌培养物的存在（定性细菌分析），显着性水平设置为p <0.05。结果：所有动物术后均良好。一只动物因经阴道通路而出现暂时性围手术期出血。手术后，Glap的两只动物和GNOTES的一只动物的血培养呈阳性。来自GNOTES和Glap的所有动物均表现出混合的抗前菌群。消毒后，一只动物（GNOTES）的阴道拭子培养呈阳性（已鉴定出单个细菌菌株）。 Glap中无阳性皮肤拭子培养。尸检时没有腹腔感染的迹象。在两只动物中，一只来自Glap，另一只来自GNOTES，腹腔内培养的棒状杆菌属菌呈阳性。和大肠杆菌。在进入部位和腹膜培养物中发现的细菌菌群之间没有相关性。结论：纯经阴道腹膜镜检查与猪肝和腹膜活检是可行的，并且与腹腔镜检查相比，细菌污染相关。术后1周后腹膜细菌污染在临床上无意义。术前消毒可大大减少经阴道和腹腔镜手术之前的细菌负荷。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号