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首页> 外文期刊>Surgical Endoscopy >Laparoscopic versus open distal splenopancreatectomy for the treatment of pancreatic body and tail cancer: A retrospective, mid-term follow-up study at a single academic tertiary care institution
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Laparoscopic versus open distal splenopancreatectomy for the treatment of pancreatic body and tail cancer: A retrospective, mid-term follow-up study at a single academic tertiary care institution

机译：腹腔镜与开放式远端脾胰切除术治疗胰腺癌和尾癌：在一家单一的三级学术机构进行的回顾性中期中期随访研究

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Background/Objective: Laparoscopic distal splenopancreatectomy (DSP) is an effective and safe surgical modality for treating benign and borderline distal pancreatic tumors, but rarely for pancreatic cancer. This study aimed to examine the feasibility, effectiveness, and safety of laparoscopic versus laparotomic DSP in pancreatic body-tail cancer (PBTC) patients. Methods: Thirty-four PBTC patients were consecutively and retrospectively hospitalized for elective laparoscopic DSP (n = 11) or laparotomy (n = 23) between January 2007 and December 2011. The primary outcome measure was mean overall survival (OS). Results: All patients underwent DSP via laparoscopy or laparotomy as scheduled and were followed-up for 12-72 months. The two groups showed statistically similar mean operative time (laparoscopy vs. laparotomy, 150 ± 54 vs. 160 ± 48 min), median volume of intraoperative bleeding (100 [50-400] vs. 150 [50-350] ml), and rate of postoperative pancreatic fistula (18.2 vs. 21.7 %). The laparoscopy group had a significantly shorter median duration of hospitalization (5 [3-12] vs. 8 [7-22] d, P < 0.05). All patients had a clear resection margin and showed statistically similar tumor size (2.8 ± 1.5 vs. 3.1 ± 1.7 cm), number of lymph nodes dissected (14.8 ± 4.5 vs. 16.1 ± 5.7), and mean OS (42.0 ± 8.6 vs. 54.0 ± 5.8 mo, P > 0.05). Conclusions: Laparoscopic DSP is a feasible, effective, and safe alternative to laparotomy in carefully selected PBTC patients and is associated with a more rapid postoperative recovery.
机译：背景/目的：腹腔镜远端脾胰切除术（DSP）是一种治疗良性和交界性远端胰腺肿瘤的有效且安全的手术方式，但很少用于胰腺癌。这项研究的目的是检查在胰腺体尾癌（PBTC）患者中，腹腔镜与腹腔镜DSP的可行性，有效性和安全性。方法：2007年1月至2011年12月，对34例PBTC患者进行了选择性腹腔镜DSP手术（n = 11）或剖腹手术（n = 23）进行了回顾性住院治疗。结果：所有患者均按计划通过腹腔镜或剖腹术接受了DSP，并随访了12-72个月。两组的平均手术时间（腹腔镜手术与开腹手术，150±54 vs. 160±48分钟），术中出血量的中位数（100 [50-400] vs. 150 [50-350] ml）在统计学上相似。术后胰瘘的发生率（18.2比21.7％）。腹腔镜检查组的中位住院时间显着缩短（5 [3-12]天，而8 [7-22]天，P <0.05）。所有患者均具有明确的切除切缘，并显示出统计学上相似的肿瘤大小（2.8±1.5 vs. 3.1±1.7 cm），解剖的淋巴结数目（14.8±4.5 vs. 16.1±5.7）和平均OS（42.0±8.6 vs. 4）。 54.0±5.8个月，P> 0.05）。结论：对于精心挑选的PBTC患者，腹腔镜DSP是开腹手术的可行，有效和安全的替代方法，并且术后恢复更快。

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