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Colorectal polyps: When should we tattoo?

机译:大肠息肉:我们什么时候应该纹身?

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Background: Current guidelines recommend tattooing of suspicious-looking lesions at colonoscopy without a reference to the size of the polyp. However, the endoscopist has to make a judgement as to which lesion may be malignant and require future localisation based on the appearance and size of the polyp. The aim of this study was to determine the relationship between endoscopic polyp size and invasive colorectal cancer so as to inform tattooing practice for patients taking part in the national bowel cancer screening programme (BCSP). Methods: Data of BCSP patients who had undergone a polypectomy between October 2008 and October 2010 were collected from a prospectively maintained hospital endoscopic database. Histology data were obtained from electronic patient records. Results: A total of 165 patients had undergone 269 polypectomies. Their median age was 66 years and 66 % were men. The mean endoscopic polyp size was 10.7 mm (SD = ±8 mm). Histologically, 81 % were neoplastic with 95 % showing low-grade and 5 % high-grade dysplasia. Eight patients were found to have invasive malignancy within their polyp. The risk of invasive malignancy within a polyp was 0.7 % (1/143) when the endoscopic polyp size was <10 mm; the risk increased to 2.4 % (2/83) when the polyp size was 10-19 mm and 13 % (5/40) when the polyp was >20 mm. This trend was statistically significant (p = 0.001). About 23 % of the patients had the site of their polyp tattooed; the mean size of the tattooed polyps was 21 mm (range = 15-50 mm). Consequently, 25 % of malignant polyps and 63 % of polyps with highgrade dysplasia were not tattooed. Conclusion: The risk of polyp cancer among BCSP patients increases significantly when the endoscopic polyp size is ≥10 mm. We recommend that all polyps ≥10 mm be tattooed.
机译:背景:目前的指南建议在结肠镜检查时对看似可疑的病变进行纹身,而不要提及息肉的大小。然而,内镜医师必须根据息肉的外观和大小判断哪个病变可能是恶性的,并要求将来进行定位。这项研究的目的是确定内窥镜息肉大小与浸润性结直肠癌之间的关系,以便为参加国家肠癌筛查计划(BCSP)的患者提供纹身实践。方法:从前瞻性维护的医院内窥镜数据库中收集2008年10月至2010年10月间行息肉切除术的BCSP患者的数据。组织学数据是从电子患者记录中获得的。结果:总共165例患者接受了269例多视镜检查。他们的中位年龄为66岁,男性为66%。内镜下息肉的平均大小为10.7毫米(SD =±8毫米)。在组织学上,81%为肿瘤性肿瘤,其中95%为低度增生,5%为高度不典型增生。发现八名患者息肉内有浸润性恶性肿瘤。当内窥镜息肉大小<10 mm时,息肉内浸润性恶性肿瘤的风险为0.7%(1/143);当息肉大小为10-19 mm时,风险增加到2.4%(2/83);当息肉> 20 mm时,风险增加到13%(5/40)。这种趋势具有统计学意义(p = 0.001)。大约23%的患者的息肉部位有纹身;刺出的息肉的平均大小为21毫米(范围= 15-50毫米)。因此,25%的恶性息肉和63%的具有高度不典型增生的息肉没有被纹身。结论:当内镜下息肉大小≥10mm时,BCSP患者中息肉癌的风险显着增加。我们建议对所有≥10 mm的息肉进行纹身。

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