...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Endoscopic stenting versus operative gastrojejunostomy for malignant gastric outlet obstruction
【24h】

Endoscopic stenting versus operative gastrojejunostomy for malignant gastric outlet obstruction

机译：内镜支架置入与手术胃空肠吻合术治疗恶性胃出口梗阻

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Malignant gastric outlet obstruction represents a terminal stage in pancreatic cancer. Between 5% and 25% of patients with pancreatic cancer ultimately experience malignant gastric outlet obstruction. The aim in palliating patients with malignant gastric outlet obstruction is to reestablish an oral intake by restoring gastrointestinal continuity. This ultimately improves their quality of life in the advanced stages of cancer. The main drawback to operative bypass is the high incidence of delayed gastric emptying, particularly in this group of patients with symptomatic obstruction. This study aimed to compare surgical gastrojejunostomy and endoscopic stenting in palliation of malignant gastric outlet obstruction, acknowledging the diversity and heterogeneity of patients with this presentation. Methods: This retrospective study investigated patients treated for malignant gastric outlet obstruction from December 1998 to November 2008 at Nepean Hospital, Sydney, Australia. Endoscopic duodenal stenting was performed under fluoroscopic guidance for placement of the stent. The operative patients underwent open surgical gastrojejunostomy. The outcomes assessed included time to diet, hospital length of stay (LOS), biliary drainage procedures, morbidity, and mortality. Results: Of the 45 participants in this study, 26 underwent duodenal stenting and 19 had operative bypass. Comparing the stenting and operative patients, the median time to fluid intake was respectively 0 vs. 7 days (P < 0.001), and the time to intake of solids was 2 vs. 9 days (P = 0.004). The median total LOS was shorter in the stenting group (11 vs. 25 days; P < 0.001), as was the median postprocedure LOS (5 vs. 10 days; P = 0.07). Conclusions: Endoscopic stenting is preferable to operative gastrojejunostomy in terms of shorter LOS, faster return to fluids and solids, and reduced morbidity and in-hospital mortality for patients with a limited life span.
机译：背景：恶性胃出口梗阻代表胰腺癌的晚期。最终，有5％至25％的胰腺癌患者会经历恶性胃出口梗阻。减轻恶性胃出口梗阻患者的目的是通过恢复胃肠道的连续性来重新建立口服摄入。这最终改善了他们在癌症晚期的生活质量。手术旁路的主要缺点是胃排空延迟的发生率很高，尤其是在有症状梗阻的这一组患者中。这项研究旨在比较胃空肠吻合术和内镜支架置入术在缓解恶性胃出口梗阻方面的作用，并承认这种表现的患者具有多样性和异质性。方法：这项回顾性研究调查了1998年12月至2008年11月在澳大利亚悉尼的Nepean医院接受过恶性胃出口梗阻治疗的患者。内窥镜十二指肠支架置入术是在荧光镜引导下进行的。手术患者接受开放性胃空肠吻合术。评估的结果包括饮食时间，住院时间（LOS），胆道引流程序，发病率和死亡率。结果：在该研究的45位参与者中，有26位接受了十二指肠支架置入术，其中19位接受了手术旁路。比较支架置入术和手术患者，进食液体的中位时间分别为0天与7天（P <0.001），固体摄入时间为2天与9天（P = 0.004）。支架置入组中位总LOS较短（11 vs. 25天; P <0.001），而术后中位LOS也很短（5 vs. 10天; P = 0.07）。结论：内镜下支架置入术比胃空肠吻合术更可取，因为它可以缩短LOS，更快地恢复体液和固体，并降低寿命有限的患者的发病率和住院死亡率。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号