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Elective laparoscopic cholecystectomy for symptomatic uncomplicated gallstone disease: Do the symptoms disappear?

机译:有症状的单纯性胆结石病的选择性腹腔镜胆囊切除术:症状消失了吗?

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Background: Symptomatic gallstone disease is considered an indication for cholecystectomy. A considerable proportion of patients may experience persistent symptoms after surgery. The purpose of the present study was to find out the rate of symptom persistence after elective laparoscopic cholecystectomy (LC) performed for symptomatic uncomplicated gallstone disease and, in particular, to clarify whether the recurrence rate differs according to the severity of preoperative symptoms. Methods: During a 10-year period (1992-2001), 1,101 patients underwent elective LC at Turku City Hospital for Surgery. A questionnaire concerning the intensity of preoperative symptoms, persistence of symptoms postoperatively, and overall satisfaction with the outcome of the procedure was sent to patients. A total of 677 patients [mean age (range) 59 (21-94) years; 554 (83.1 %) females] with uncomplicated gallstone disease returned the completed form. Results: Overall, 380 (57 %) patients reported attacks of intense upper abdominal pain, and 287 (43 %) reported episodic mild abdominal symptoms as the prevailing preoperative symptom. Two hundred and forty-eight (37 %) patients continued to have abdominal symptoms after the operation. Among those with predominantly mild abdominal symptoms preoperatively, 119 (41 %) reported the persistence of symptoms after the operation, while in the group with mainly severe upper abdominal pain attacks, 129 (33 %) patients had recurrences (p = 0.052). Conclusions: According to our data, more than one-third of patients with symptomatic uncomplicated gallstone disease experienced persistent symptoms after elective LC. Patients with mild preoperative symptoms seemed to have more recurrences than those with severe symptoms, although the difference was not statistically significant.
机译:背景:有症状的胆结石病被认为是胆囊切除术的适应症。相当多的患者术后可能会出现持续的症状。本研究的目的是找出有症状的无并发症胆结石病患者进行选择性腹腔镜胆囊切除术(LC)后的症状持续率,尤其是要弄清楚复发率是否因术前症状的严重程度而有所不同。方法:在十年期间(1992年至2001年),在图尔库市外科医院接受了1,101例患者的选择性LC治疗。向患者发送了有关术前症状强度,术后症状持续性以及对手术结果总体满意度的问卷。共有677名患者[平均年龄(范围)59(21-94)岁; 554例(83.1%的女性)患有单纯性胆结石病,返回完整表格。结果:总体上,有380名(57%)患者报告了剧烈的上腹部疼痛发作,而287名(43%)患者报告了发作性轻度腹部症状为主要的术前症状。 248名(37%)患者在手术后继续出现腹部症状。术前腹部症状以轻度为主的患者中,有119名(41%)术后症状持续存在,而以严重上腹痛发作为主的组中,有129名患者(33%)复发(p = 0.052)。结论:根据我们的数据,有症状的单纯性胆结石病患者中有三分之一以上在选择性LC后出现持续症状。轻度术前症状的患者似乎比重度症状的患者复发更多,尽管差异无统计学意义。

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