Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases

Kumara H. M. C. Shantha; Gaita David J.; Miyagaki Hiromichi; Yan Xiaohong; Herath Sonali A. C.; Cekic Vesna; Whelan Richard L.

首页> 外文期刊>Surgical Endoscopy >Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases

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Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases

机译：微创结直肠切除术与术后第一个月血浆基质金属蛋白酶3（MMP-3）的水平显着升高有关，这可能促进残留转移的生长

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MMP-3, a member of the matrix metalloproteinase (MMP) family, is involved in the breakdown of the extracellular matrix in tissue remodeling and may also play a role in cancer progression and metastasis. Minimally invasive colorectal resection (MICR) may increase plasma MMP-3 levels directly via surgical trauma or indirectly due to surgery-associated elevations in TNF-alpha and IL1 which are regulators of MMP-3. This study's purpose was to evaluate plasma MMP-3 levels during the first month after MICR for colorectal cancer.

机译：MMP-3是基质金属蛋白酶（MMP）家族的成员，在组织重塑中参与细胞外基质的分解，并且也可能在癌症的进展和转移中起作用。微创结直肠切除术（MICR）可能直接通过手术创伤或由于与手术相关的作为MMP-3调节因子的TNF-alpha和IL1升高而间接升高血浆MMP-3水平。这项研究的目的是评估大肠癌MICR后第一个月的血浆MMP-3水平。

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《Surgical Endoscopy》 |2014年第12期|共7页
作者
Kumara H. M. C. Shantha; Gaita David J.; Miyagaki Hiromichi; Yan Xiaohong; Herath Sonali A. C.; Cekic Vesna; Whelan Richard L.;
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正文语种 eng
中图分类诊断学;
关键词
Matrix metalloproteinase 3; Minimally invasive colorectal surgery;

机译：基质金属蛋白酶3;微创结直肠手术;

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1. Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases [J] . Kumara H. M. C. Shantha, Gaita David J., Miyagaki Hiromichi, Surgical Endoscopy . 2014,第12期

机译：微创结直肠切除术与术后第一个月血浆基质金属蛋白酶3（MMP-3）的水平显着升高有关，这可能促进残留转移的生长
2. Plasma levels of the proangiogenic protein CXCL16 remains elevated for 1?month after minimally invasive colorectal cancer resection [J] . H. M. C. Shantha Kumara, Erica Pettke, Abhinit Shah, World Journal of Surgical Oncology . 2018,第1期

机译：微创结直肠癌切除术后1个月，血浆中促血管生成蛋白CXCL16的水平仍保持升高
3. Persistent elevation of plasma vascular endothelial growth factor levels during the first month after minimally invasive colorectal resection [J] . A. Belizon, E. Balik, P. Horst, Surgical Endoscopy . 2008,第2期

机译：微创结直肠癌切除术后第一个月血浆血管内皮生长因子水平持续升高
4. Surgical diamond wheels for minimally invasive surgery in bone resection under saline supply [C] . Takeru Mizutani, Toshiyuki Enomoto, Urara Satake CIRP International Conference on High Performance Cutting . 2018

机译：盐水供应下骨切除术中微创手术的外科钻石轮
5. Protein kinase C regulation of matrix metalloproteinases and invasive growth in glioblastoma multiforme. [D] . Kohutek, Zachary Adam. 2009

机译：多种形式的胶质母细胞瘤中基质金属蛋白酶和侵袭性生长的蛋白激酶C调节。
6. Plasma interleukin-8 levels are persistently elevated for 1 month after minimally invasive colorectal resection for colorectal cancer [O] . H. M.C. Shantha Kumara, Elli Sutton, Geoffrey A. Bellini, -1

机译：结肠直肠癌微创切除术后1个月血浆白细胞介素8水平持续升高
7. Plasma levels of the proangiogenic protein CXCL16 remains elevated for 1 month after minimally invasive colorectal cancer resection [O] . H. M. C. Shantha Kumara, Erica Pettke, Abhinit Shah, 2018

机译：在微创结直肠癌切除术后1个月后，血浆蛋白CXCL16的血浆水平仍升高1个月

Minimally invasive colorectal resection is associated with significantly elevated levels of plasma matrix metalloproteinase 3 (MMP-3) during the first month after surgery which may promote the growth of residual metastases

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