首页> 外文期刊>Surgical Endoscopy >Transgastric cecectomy in canine models: natural orifice transluminal endoscopic surgery (NOTES).
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Transgastric cecectomy in canine models: natural orifice transluminal endoscopic surgery (NOTES).

机译:犬模型中的经胃大肠切除术:自然孔腔内镜手术(NOTES)。

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BACKGROUND: Natural orifice transluminal endoscopic surgery (NOTES) for bowel resection is a challenging procedure. We studied the feasibility and safety of NOTES by performing cecectomy in dogs, which is equivalent to simple bowel resection in man. METHODS: Three dogs underwent transgastric endoscopic cecectomy with laparoscopic assistance. Antibiotics and irrigation were administered as preoperative preparation. A single-channel endoscope was introduced through the stomach into the peritoneal cavity, and the cecum was dissected and ligated with an L-knife and endoloops, respectively. Laboratory blood testing, peritoneal bacterial culture, and radiologic testing were performed perioperatively. Animals underwent autopsies on postoperative day (POD) 14. RESULTS: All subjects survived surgery and remained alive until POD 14. Mean operative time was 126.6 min. The absence of bacterial infections and anatomic leaks was verified by peritoneal swap culture, blood count, air leak testing, and bowel contrast radiology. However, a temporary mild elevation in white blood cell count was noted. No abscess or sign of infection was observed during autopsy, although adhesion was evident. CONCLUSIONS: Transgastric endoscopic cecectomy with minimal laparoscopic assistance is a feasible and safe procedure. Cecectomy in dogs is equivalent to procedures such as appendectomy, resection of Meckel's diverticulum, and oophorectomy in man. Natural orifice transluminal endoscopic surgery could prove to be a good optional surgical procedure.
机译:背景:自然孔腔内镜手术(NOTES)用于肠切除术是一项具有挑战性的手术。我们通过在狗中进行大肠切除术研究了NOTES的可行性和安全性,这等效于人的简单肠切除术。方法:三只狗在腹腔镜辅助下进行了经胃内镜盲肠切除术。术前准备抗生素和冲洗。通过胃将单通道内窥镜插入腹膜腔,解剖盲肠并分别用L型刀和内环结扎。围手术期进行实验室血液检查,腹膜细菌培养和放射学检查。在术后第14天对动物进行尸检。结果:所有受试者均在手术后幸存并存活直至POD14。平均手术时间为126.6分钟。通过腹膜置换培养,血细胞计数,漏气测试和肠造影放射学证实无细菌感染和解剖学渗漏。但是,注意到白细胞计数暂时升高。尽管有明显的粘连,但在尸检期间未观察到脓肿或感染迹象。结论腹腔镜辅助下经胃内镜大肠切除术是一种可行且安全的方法。狗的结肠切除术等同于诸如阑尾切除术,Meckel憩室切除术和人的卵巢切除术之类的手术。天然小孔腔内镜手术可以证明是一种很好的可选手术方法。

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