• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Tissue apposition system: new technology to minimize surgery for endoscopically unresectable colonic polyps.
【24h】

Tissue apposition system: new technology to minimize surgery for endoscopically unresectable colonic polyps.

机译：组织并置系统：一种新技术，可最大程度减少内窥镜下无法切除的结肠息肉的手术。

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: This is the first clinical series using the Tissue Apposition System (TAS) device in a feasibility study of polypectomy as an alternative to laparoscopic colectomy (LC) for endoscopically unresectable polyps. TAS is a novel T-tag system for endoscopic placement of sutures, facilitating closure of larger defects from advanced endoluminal or transluminal endoscopic procedures. Such novel instrumentation may reduce risk and accelerate recovery. METHODS: After institutional review board approval, patients with endoscopically unresectable polyps who would otherwise require LC were enrolled. The polyp site was visualized by colonoscopy and resected with laparoscopic assistance, using endoscopic mucosal resection (EMR) or submucosal dissection. After confirming benign disease by frozen section, the polypectomy site was closed by TAS under laparoscopic observation to avoid injury to surrounding structures. Follow-up colonoscopy was performed at 3 months. RESULTS: Seven patients were recruited (5 men; mean age, 66 years). Polyps were from 20 to 50 (mean, 30) mm in diameter; six were in the right colon, and three were on the mesenteric border of the bowel. All final pathology was benign. Mean EMR time was 29 min, mean time taken for TAS was 37 min, and mean total operative time was 199 min. Two TAS procedures required conversion to LC (one unresectable polyp and one device failure). Five TAS procedures were completed, with a mean hospital stay of 1.2 days, and no complications. Follow-up colonoscopy revealed healing without polyp recurrence in any case. One patient (initial 5-cm sigmoid polyp) developed a very mild clinically asymptomatic stricture in the sigmoid colon. CONCLUSIONS: This initial human experience demonstrates that TAS can be used safely in the colon under laparoscopic control. TAS permits safe closure of defects after endoscopic polypectomy of selected and otherwise unresectable polyps. Such technology may potentially avoid the need for LC and permit rapid recovery with short hospital stay.
机译：目的：这是在息肉切除术的可行性研究中使用组织定位系统（TAS）装置替代内窥镜下不能切除的息肉的腹腔镜结肠切除术（LC）的第一个临床系列。 TAS是用于内窥镜缝合线放置的新型T标签系统，有助于封闭来自先进的腔内或腔内镜检查程序的较大缺陷。这种新颖的仪器可以降低风险并加速恢复。方法：经过机构审查委员会的批准，纳入了否则需要LC的内镜下无法切除的息肉患者。通过结肠镜检查可以看到息肉部位，并使用内窥镜黏膜切除术（EMR）或黏膜下剥离术在腹腔镜辅助下切除。通过冰冻切片确认良性疾病后，在腹腔镜观察下用TAS关闭息肉切除部位，以免损伤周围结构。在3个月时进行结肠镜检查。结果：招募了7名患者（5名男性;平均年龄66岁）。息肉的直径为20到50（平均30）毫米。六个在右结肠，三个在肠系膜边界。所有的最终病理都是良性的。平均EMR时间为29分钟，TAS平均时间为37分钟，平均总手术时间为199分钟。两种TAS程序需要转换为LC（一种无法切除的息肉和一种设备故障）。完成了五项TAS程序，平均住院时间为1.2天，无并发症。结肠镜检查显示，无论如何，息肉均无复发。一名患者（最初的5 cm乙状结肠息肉）在乙状结肠中出现了非常轻微的临床无症状性狭窄。结论：最初的人类经验表明，TAS可以在腹腔镜控制下安全地用于结肠。 TAS可以在内窥镜下切除某些无法切除的息肉后安全闭合缺损。这种技术可以潜在地避免对LC的需求，并允许在短暂的住院时间内快速恢复。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号