BACKGROUND: Single-port laparoscopic surgery is increasingly used to treat various types of diseases requiring surgical intervention. We present the technique and the results of our simple "cross and twine" intracorporeal knotting approach for treatment of a perforated duodenal ulcer. METHODS: From January 2009 to October 2009, 13 patients with perforated duodenal ulcers underwent single-port laparoscopic repair. The laparoscopic procedure included peritoneal lavage and suture of the perforation. The omentum above the repair site was then reinforced. After surgery, patients took an H2 receptor antagonist for 8 weeks and then underwent follow-up gastrofiberscopy. RESULTS: All procedures were completed under the conditions described. The mean operative time was 90.2 +/- 24.2 min, and the mean hospital stay was 6.1 +/- 0.5 days. The mean number of times that opiates were used for pain was 0.5 +/- 1.0, and wound length was 1.9 +/- 0.1 cm. There was no operation-related morbidity. Follow-up gastrofiberscopy revealed good lesion healing. CONCLUSIONS: Single-port laparoscopic repair using the "cross and twine" knotting technique is a feasible and safe procedure, and it may be a less invasive laparoscopic surgical technique for scarless surgical treatment of perforated duodenal ulcers.
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