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首页> 外文期刊>Surgical Endoscopy >Transgastric pure-NOTES peritoneoscopy and endoscopic ultrasonography for staging of gastrointestinal cancers: A survival and feasibility study
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Transgastric pure-NOTES peritoneoscopy and endoscopic ultrasonography for staging of gastrointestinal cancers: A survival and feasibility study

机译：经胃纯净NOTES腹膜镜和内镜超声检查对胃肠道癌的分期：生存和可行性研究

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Background Human natural orifice transluminal endoscopic surgery (NOTES) has mainly been based on simultaneous laparoscopic assistance (hybrid NOTES), forgoing the theoretical benefits of the NOTES technique. This is due to a lack of NOTES-specific instruments and endoscopes, making pure-NOTES procedures difficult and time consuming. An area where pure NOTES could be adopted at its present stage of development is minimally invasive staging of gastrointestinal (GI) cancer. The aim of this study is to evaluate the feasibility of combining transgastric (TG) pure-NOTES peritoneoscopy and intraperitoneal endoscopic ultrasonography (ip-EUS) with intraluminal EUS (il-EUS) for peritoneal evaluation. Methods This was a feasibility and survival study where il-EUS followed by ip-EUS and peritoneoscopy was performed in 10 pigs subjected to TG pure NOTES. A score was given with regard to achieved visualisation of predefined anatomical structures. Survival was assessed at postoperative day (POD) 14. Results All animals survived until POD 14. Median total procedural time was 94 min (range 74-130 min). Median time for il-EUS, ip-EUS and peritoneoscopy was 11 min (range 7-14 min), 13 min (range 8-20 min) and 10 min (range 6-23 min). Il-EUS, ip-EUS and peritoneoscopy resulted in a score of 15/15 points (range 14-15 points), 6/9 points (range 1-8 points) and 12/13 points (range 8-13 points). Conclusions TG pure-NOTES peritoneoscopy and ip-EUS combined with il-EUS is feasible and provides sufficient peritoneal evaluation. The technique could have potential for minimally invasive staging of GI cancers.
机译：背景技术人的自然孔腔内镜手术（NOTES）主要基于同时腹腔镜辅助（混合型NOTES），从而放弃了NOTES技术的理论优势。这是由于缺少NOTES专用的仪器和内窥镜，使得纯NOTES程序困难且耗时。在目前的发展阶段可以采用纯NOTES的领域是胃肠道（GI）癌的微创分期。这项研究的目的是评估结合经胃（TG）的纯净NOTES腹膜镜检查和腹腔内超声检查（ip-EUS）与腔内EUS（il-EUS）进行腹膜评估的可行性。方法这是一项可行性和生存性研究，其中il-EUS，ip-EUS和腹膜镜检查在10只经TG纯NOTES治疗的猪中进行。在实现预定义解剖结构的可视化方面给出了一个分数。术后第14天评估生存率。结果所有动物均存活至POD14。中位总手术时间为94分钟（74-130分钟）。 il-EUS，ip-EUS和腹膜镜检查的中位时间为11分钟（7-14分钟），13分钟（8-20分钟）和10分钟（6-23分钟）。 Il-EUS，ip-EUS和腹膜镜检查的得分分别为15/15分（14-15分），6/9分（1-8分）和12/13分（8-13分）。结论TG pure-NOTES腹膜镜和ip-EUS联合il-EUS是可行的，并提供了充分的腹膜评估。该技术可能对胃肠道癌的微创分期具有潜力。

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