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首页> 外文期刊>Surgical Endoscopy >In vivo MRI visualization of mesh shrinkage using surgical implants loaded with superparamagnetic iron oxides.
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In vivo MRI visualization of mesh shrinkage using surgical implants loaded with superparamagnetic iron oxides.

机译:使用装载超顺磁性氧化铁的手术植入物进行的体内MRI网格收缩观察。

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摘要

Prosthetic mesh implants are widely used in hernia surgery. To show long-term mesh-related complications such as shrinkage or adhesions, a precise visualization of meshes and their vicinity in vivo is important. By supplementing mesh fibers with ferro particles, magnetic resonance imaging (MRI) can help to delineate the mesh itself. This study aimed to demonstrate and quantify time-dependent mesh shrinkage in vivo by MRI.Polyvinylidenfluoride (PVDF) meshes with incorporated superparamagnetic iron oxides (SPIOs) were implanted as an abdominal wall replacement in 30 rats. On days 1, 7, 14, or 21, MRI was performed using a gradient echo sequence with repetition time (TR)/echo time (TE) of 50/4.6 and a flip angle of 20°. The length, width, and area of the device were measured on axial, coronal, and sagittal images, and geometric deformations were assessed by surgical explantation.In all cases, the meshes were visualized and their area estimated by measuring the length and width of the mesh. The MRI presented a mean area shrinkage in vivo of 13% on day 7, 23% on day 14, and 23% on day 21. Postmortem measurements differed statistically from MRI, with a mean area shrinkage of 23% on day 7, 28% on day 14, and 30% on day 21. Ex vivo measurements of shrinkage showed in vivo measurements to be overestimated approximately 8%. Delineation of the mesh helped to show folding or adhesions close to the intestine.Loading of surgical meshes with SPIOs allows their precise visualization during MRI and guarantees an accurate in vivo assessment of their shrinkage. The authors' observation clearly indicates that shrinkage in vivo is remarkably less than that shown by illustrated explantation measurements. The use of MRI with such meshes could be a reliable technique for checking on proper operation of implanted meshes and showing related complications, obviating the need for exploratory open surgical revision.
机译:人工网状植入物广泛用于疝气手术。为了显示与网格相关的长期并发症,例如收缩或粘连,在体内精确显示网格及其附近区域非常重要。通过在铁网纤维上添加铁颗粒,磁共振成像(MRI)可以帮助勾勒出铁网本身的轮廓。这项研究旨在通过MRI证实和量化体内随时间变化的网格收缩。将30种大鼠植入结合了超顺磁性氧化铁(SPIO)的聚偏二氟乙烯(PVDF)网格作为腹壁替代物。在第1、7、14或21天,使用梯度回波序列(重复时间(TR)/回波时间(TE)为50 / 4.6和翻转角为20°)执行MRI。在轴向,冠状和矢状位图像上测量器械的长度,宽度和面积,并通过外科手术植入评估几何变形。在所有情况下,均可以通过目测网格的长度和宽度来对网格进行可视化并估计其面积网格。 MRI显示第7天的体内平均面积缩小为13%,第14天为23%,第21天为23%。验尸测量结果与MRI有所不同,第7天的平均面积缩小为23%,28%在第14天时的收缩率是30%,在第21天时的收缩率是30%。筛网的轮廓有助于显示靠近肠道的折叠或粘连。带有SPIO的外科筛网加载可以在MRI期间对其进行精确可视化,并确保对其收缩情况进行准确的体内评估。作者的观察清楚地表明,体内的收缩率显着小于插图中所示的移植测量值。将MRI与此类网孔配合使用可能是一种可靠的技术,可用于检查植入的网孔是否正常运行并显示相关并发症,从而无需进行探索性开放式手术翻修。

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