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Clinical outcomes of laparoscopic surgery for advanced transverse and descending colon cancer: A single-center experience

机译:腹腔镜手术治疗晚期横结肠癌和降结肠癌的临床结果:单中心经验

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Background The role of laparoscopic surgery in management of transverse and descending colon cancer remains controversial. The aim of the present study is to investigate the short-term and oncologic long-term outcomes associated with laparoscopic surgery for transverse and descending colon cancer. Methods This cohort study analyzed 245 patients (stage II disease, n = 70; stage III disease, n = 63) who underwent resection of transverse and descending colon cancers, including 200 laparoscopic surgeries (LAC) and 45 conventional open surgeries (OC) from December 1996 to December 2010. Short-term and oncologic long-term outcomes were recorded. Results The operative time was longer in the LAC group than in the OC group. However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group. The 5-year overall and disease-free survival rates for patients with stage II were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively. The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively. Conclusion Use of laparoscopic surgery resulted in acceptable short-term and oncologic outcomes in patients with advanced transverse and descending colon cancer.
机译:背景腹腔镜手术在处理结肠癌和降结肠癌中的作用仍存在争议。本研究的目的是研究与腹腔镜手术治疗横结肠癌和降结肠癌相关的短期和肿瘤远期结局。方法该队列研究分析了245例行横断和降结肠癌切除术的患者(II期疾病,n = 70; III期疾病,n = 63),包括200例腹腔镜手术(LAC)和45例常规开放手术(OC)。记录1996年12月至2010年12月的短期和肿瘤长期结局。结果LAC组手术时间比OC组更长。然而,与OC组相比,LAC组的术中失血量明显降低,术后恢复时间明显缩短。 OC组II期患者的5年总体生存率和无病生存率分别为OC组和LAC组,分别为84.9%和84.9%和93.7%和90.0%。 OC组和LAC组的III期疾病患者的5年总体生存率和无病生存率分别为63.4%和54.6%。结论腹腔镜手术可使晚期横结肠癌和降结肠癌患者的短期和肿瘤学结局均可接受。

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