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首页> 外文期刊>Surgical Endoscopy >Testicular functions, chronic groin pain, and quality of life after laparoscopic and open mesh repair of inguinal hernia: a prospective randomized controlled trial.
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Testicular functions, chronic groin pain, and quality of life after laparoscopic and open mesh repair of inguinal hernia: a prospective randomized controlled trial.

机译:腹股沟疝腹腔镜和开放网膜修复后的睾丸功能,慢性腹股沟疼痛和生活质量:一项前瞻性随机对照试验。

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摘要

Laparoscopic inguinal hernia repair is still not the gold standard for patients with inguinal hernia. The aim of this study was to compare testicular dysfunction, incidence and factors influencing chronic groin pain, and quality of life after laparoscopic and open mesh repair.One hundred twenty patients were studied in a prospective randomized trial. One hundred seventeen patients completed the required follow-up, 60 following laparoscopic repair and 57 following open repair. Testicular functions were assessed by testicular volume, blood flow, and hormones, and quality of life was assessed with Short Form 36 version 2 preoperatively and postoperatively at 3 months. Pain was assessed at different time intervals preoperatively and postoperatively.Preoperative profiles of both groups were well matched. A significant decrease in testicular volume (p = 0.01) and less improvement in blood flow (p = 0.048) was seen after open repair. There was also a significant reduction in serum testosterone level (p = 0.02) with a significant increase in FSH and LH level (p < 0.001); however, there was no testicular atrophy. Incidence and severity of chronic groin pain were significantly less after laparoscopic repair during normal and strenuous activities, though they were similar to those after open repair during rest after 3 months postoperatively. Age, preoperative pain, pain at 1 week, and open repair were found to be independent risk factors for chronic pain on multivariate analysis. Quality of life was significantly better postoperatively in terms of physical functions, role physical, bodily pain, and general health after laparoscopic repair.Laparoscopic repair seems favorable in terms of better preservation of testicular functions, lower incidence of acute and chronic groin pain, and significant improvement in quality of life when compared to open repair. Younger age, preoperative pain, pain after 1 week postoperatively, and open mesh repair were found to be significant risk factors for chronic groin pain.
机译:腹腔镜腹股沟疝修补术仍不是腹股沟疝患者的金标准。这项研究的目的是比较腹腔镜和开放式网状修复术后睾丸功能障碍,睾丸功能障碍的发生率,影响慢性腹股沟疼痛的因素以及生活质量。一项前瞻性随机试验研究了120例患者。 117例患者完成了所需的随访,其中腹腔镜修复60例,开放性修复57例。通过睾丸体积,血流量和激素评估睾丸功能,并在术前和术后3个月使用Short Form 36第2版评估生活质量。在术前和术后的不同时间间隔对疼痛进行评估。两组的术前情况非常吻合。开放修复后,睾丸体积明显减少(p = 0.01),血流改善较少(p = 0.048)。血清睾丸激素水平也显着降低(p = 0.02),而FSH和LH水平显着升高(p <0.001);但是,没有睾丸萎缩。在正常和剧烈活动中,腹腔镜修补后慢性腹股沟痛的发生率和严重程度明显降低,尽管与术后3个月休息时进行开放式修补相似。在多因素分析中,年龄,术前疼痛,1周疼痛和开放性修复是慢性疼痛的独立危险因素。腹腔镜修复术后的生活质量在身体功能,生理机能,身体疼痛和总体健康方面显着改善;在更好地保留睾丸功能,降低急,慢性腹股沟痛的发生率和显着性方面,腹腔镜修复似乎是有利的与开放维修相比,生活质量得到改善。年龄较小,术前疼痛,术后1周后疼痛以及网状修复是慢性腹股沟疼痛的重要危险因素。

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