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Magnifying endoscopy for diagnosis of residual/local recurrent gastric neoplasms after previous endoscopic treatment

机译:放大内窥镜诊断先前内镜治疗后残留/局部复发的胃肿瘤

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Background: Incomplete resection of gastric neoplasms by endoscopic treatment could lead to residual/local recurrence, which may be difficult to identify. This study aimed to evaluate the usefulness of magnifying endoscopy for identifying and demarcating residual/local recurrent gastric neoplasms after endoscopic treatment. Methods: Between December 2004 and November 2010, magnifying endoscopy was performed in 15 patients with residual/local recurrent gastric neoplasms. All patients underwent conventional magnifying endoscopy (CME) and enhanced-magnification endoscopy with acetic acid instillation (EME) after conventional endoscopy (CE). Eleven patients additionally underwent magnifying endoscopy using narrow-band imaging (NBI-ME) and a combination of narrow-band imaging and acetic acid instillation (NBI-EME). For each procedure, it was recorded whether the location and circumferential demarcation of the lesions were identified. All lesions were resected by endoscopic submucosal dissection. Results Eleven lesions were identified using CE. However, two and four additional lesions were identified using CME and EME, respectively. In 11 cases, NBI-ME and NBI-EME were performed and all lesions were identified. Three lesions, which were identified by CME, were not demarcated circumferentially. All 15 lesions were well demarcated by EME and 11 by NBI-ME and NBI-EME. Of the resected specimens, histopathology indicated that ten lesions were differentiated tubular adenocarcinomas and five lesions were adenomas. The histopathological diagnosis of the location and demarcation of all neoplasms corresponded to endoscopic findings. Conclusions: Magnifying endoscopy techniques (CME, EME, NBI-ME, and NBI-EME) may be useful for identifying and demarcating residual/local recurrent gastric neoplasms after previous endoscopic treatment.
机译:背景:通过内窥镜治疗未完全切除胃肿瘤可能导致残留/局部复发,这可能很难确定。这项研究旨在评估内窥镜治疗后放大内窥镜对识别和标定残余/局部复发胃肿瘤的有用性。方法:2004年12月至2010年11月,对15例残留/局部复发的胃肿瘤患者进行了放大内镜检查。所有患者在常规内窥镜检查(CE)后均接受常规放大内窥镜检查(CME)和增强放大内窥镜检查,并加注乙酸(EME)。另外有11例患者使用窄带成像(NBI-ME)以及窄带成像和乙酸滴注(NBI-EME)的组合进行了放大内窥镜检查。对于每个程序,记录是否确定了病变的位置和周界。所有病变均通过内镜下黏膜下切除术切除。结果使用CE鉴定出11个病变。但是,分别使用CME和EME鉴定出另外两个和四个病变。在11例中,进行了NBI-ME和NBI-EME并发现了所有病变。 CME识别出的三个病变未在圆周上划定。 EME对所有15个病变进行了很好的划分,NBI-ME和NBI-EME对11个进行了很好的划分。在切除的标本中,组织病理学表明,十个病变是分化的肾小管腺癌,五个病变是腺瘤。所有肿瘤的位置和分界的组织病理学诊断与内窥镜检查结果相对应。结论:放大内窥镜检查技术(CME,EME,NBI-ME和NBI-EME)可能有助于鉴定和划分先前内镜治疗后残留/局部复发的胃肿瘤。

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