Development of a non-blurring, dual-imaging tissue marker for gastrointestinal tumor localization

Hayashi Hideki; Toyota Taro; Goto Shoichi; Ooishi Aki; Gao Tao; Ee Lau Bik; Hatayama Hirosuke; Nomoto Tomonori; Fujinami Masanori; Matsubara Hisahiro

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Development of a non-blurring, dual-imaging tissue marker for gastrointestinal tumor localization

机译：开发用于胃肠道肿瘤定位的不模糊，双成像组织标记

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Knowing the exact location of gastrointestinal tumors both preoperatively and intraoperatively is essential for planning and performing laparoscopic surgery. Different techniques have been introduced to ascertain tumor locations during surgery, but none of these are fully satisfactory at establishing the minimum margins for organ resection while retaining curability. A new, non-blurring tissue marker, detectable by both X-ray computed tomography (CT) and near-infrared (NIR) fluorescence laparoscopy, has been developed, and we here examine its utility using an animal model.

机译：术前和术中了解胃肠道肿瘤的确切位置对于计划和进行腹腔镜手术至关重要。已经引入了不同的技术来确定手术过程中的肿瘤位置，但是在保持可治愈性的同时，在建立器官切除的最小切缘方面，这些技术都不是完全令人满意的。已经开发出了一种新的，不模糊的组织标记物，该标记物可以通过X射线计算机断层扫描（CT）和近红外（NIR）荧光腹腔镜检查来检测，我们在这里使用动物模型来检验其实用性。

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《Surgical Endoscopy》 |2015年第6期|共7页
作者
Hayashi Hideki; Toyota Taro; Goto Shoichi; Ooishi Aki; Gao Tao; Ee Lau Bik; Hatayama Hirosuke; Nomoto Tomonori; Fujinami Masanori; Matsubara Hisahiro;
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正文语种 eng
中图分类诊断学;
关键词
Indocyanine green; Lipiodol (R); Near-infrared fluorescent dye; Liposome; Giant vesicle;

机译：吲哚菁绿;Lipiodol（R）;近红外荧光染料;脂质体;巨泡;

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专利

1. Development of a non-blurring, dual-imaging tissue marker for gastrointestinal tumor localization [J] . Hayashi Hideki, Toyota Taro, Goto Shoichi, Surgical Endoscopy . 2015,第6期

机译：开发用于胃肠道肿瘤定位的不模糊，双成像组织标记
2. Use of smooth muscle markers is better than the endothelial cell markers for identification of tumor venous invasion and extramural tumor deposits in gastrointestinal tract tumors [J] . Prasenjit Das, Vandana Baloda Indian Journal of Pathology and Microbiology . 2020,第1期

机译：使用平滑肌标记比内皮细胞标志物更好，用于鉴定胃肠道肿瘤中的肿瘤静脉侵袭和露营肿瘤沉积物
3. Role of novel marker discovered on gastrointestinal stromal tumor 1 in evaluation of gastrointestinal stromal tumors [J] . Farhat Abbas, Syed Besina, Summyia Farooq, Indian Journal of Medical and Paediatric Oncology . 2019,第2期

机译：在胃肠道间质瘤中发现的新型标记物1在评估胃肠道间质瘤中的作用
4. Development of a tactile robot for tumor detection and localization in biological liver tissue [C] . Farahnak M., Keshavarz M., Mojra A., 2014 International Conference on Robotics and Mechatronics . 2014

机译：开发用于生物肝组织中肿瘤检测和定位的触觉机器人
5. Localization of the APC tumor suppressor protein in neurons and identification of a novel oligodendrocyte marker. [D] . Brakeman, Jennifer Suzanne Fosnaugh. 1998

机译：APC抑癌蛋白在神经元中的定位和新型少突胶质细胞标记物的鉴定。
6. Development and Validation of a Prognostic Nomogram for Recurrence-Free Survival after Complete Surgical Resection of Localized Primary Gastrointestinal Stromal Tumor (GIST): A Retrospective Analysis [O] . Jason S. Gold, Mithat Gönen, Antonio Gutiérrez, -1

机译：完全手术切除局部胃肠肿瘤（GIST）后复发存活后预后存活率的开发和验证：回顾性分析
7. Final analysis of the randomized trial on imatinib as an adjuvant in localized gastrointestinal stromal tumors (GIST) from the EORTC Soft Tissue and Bone Sarcoma Group (STBSG), the Australasian Gastro-Intestinal Trials Group (AGITG), UNICANCER, French Sarcoma Group (FSG), Italian Sarcoma Group (ISG), and Spanish Group for Research on Sarcomas (GEIS)☆ [O] . P.G. Casali, A. Le Cesne, A.P. Velasco, 2021

机译：从EORTC软组织和骨质肉瘤组（StBSG），澳大利亚胃肠 - 试验组（Agitger），Unicancer，法国Sarcoma集团（FSG）中的随机胃肠基质肿瘤（GIST）随机试验中的临床分析。），意大利赛马赛集团（ISG），以及Spanish Group关于Sarcomas（Geis）☆

Development of a non-blurring, dual-imaging tissue marker for gastrointestinal tumor localization

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