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Hiatal hernia and gastroesophageal reflux: Study of collagen in the phrenoesophageal ligament

机译:食管裂孔疝和胃食管反流:肾食管韧带中胶原蛋白的研究

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摘要

Gastroesophageal reflux disease (GERD) is defined by the intensity and/or quality of the reflux of gastric or duodenal contents into the esophagus. Surgical treatment of GERD has shown conflicting results and unacceptable recurrence rates, mainly due to herniation of the antireflux valve into the chest. A variety of techniques has been proposed to reduce GERD recurrence, including routine use of prosthesis in cruroplasty. The prevalence of GERD in patients with hiatal hernia (HH) can reach 94 %. It is possible that the phrenoesophageal ligament (POL) engaged in the stabilization of the gastroesophageal junction in the abdomen may be an etiological factor of HH. We conducted a study to evaluate collagen in the constitution of the POL in patients with HH and cadavers without HH.
机译:胃食管反流病(GERD)由胃或十二指肠内容物反流至食道的强度和/或质量来定义。 GERD的外科治疗显示出矛盾的结果和不可接受的复发率,这主要是由于抗反流瓣膜突出进入胸腔所致。已经提出了多种减少GERD复发的技术,包括在整形手术中常规使用假体。食管裂孔疝(HH)患者的GERD患病率可达到94%。可能导致腹部食管连接处稳定的食管韧带(POL)可能是HH的病因。我们进行了一项研究,以评估患有HH和没有HH的尸体患者的POL构成中的胶原蛋白。

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