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首页> 外文期刊>Surgical Endoscopy >Microsphere intestinal blood flow analysis during pneumoperitoneum using carbon dioxide and helium.
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Microsphere intestinal blood flow analysis during pneumoperitoneum using carbon dioxide and helium.

机译：气腹中使用二氧化碳和氦气进行微球肠道血流分析。

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BACKGROUND: Pneumoperitoneum has been associated with a decreased flow in the superior mesenteric artery and portal venous system. Intestinal blood flow was studied during a 2-h pneumoperitoneum with carbon dioxide (CO2) or helium in a porcine model using colored microspheres. METHODS: For this study, 12 pigs were divided into two groups (6 CO2 and 6 helium). Different colored microspheres were injected directly into the left ventricle before, 40, 80, and 120 min after insufflation with either gas at a pressure of 15 mmHg. Microsphere concentration was measured in the mucosa and muscularis/serosa layers of the jejunum, cecum, and sigmoid colon to calculate blood flow. RESULTS: Intestinal perfusion initially increases with insufflation and returns to near baseline levels during pneumoperitoneum of 2 h. The effect of helium on tissue perfusion is similar to that of carbon dioxide. CONCLUSIONS: Intestinal perfusion does not change significantly during prolonged pneumoperitoneum at a pressure of 15 mmHg with CO2 or helium.
机译：背景：气腹与肠系膜上动脉和门静脉系统血流减少有关。使用彩色微球在猪模型中用二氧化碳（CO2）或氦气在2 h气腹中研究了肠道血流量。方法：为了进行这项研究，将12头猪分为两组（6个CO2和6个氦气）。在用15 mmHg的压力吹入任何一种气体之前，之后40、80和120分钟，将不同颜色的微球直接注射到左心室。测量空肠，盲肠和乙状结肠的粘膜和肌层/浆膜层中的微球浓度，以计算血流量。结果：肠灌注最初随着吹气而增加，并在2 h的气腹中恢复到接近基线水平。氦对组织灌注的影响与二氧化碳相似。结论：在15 mmHg的CO2或氦气长时间的气腹中，肠灌注没有明显变化。

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