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Long-term outcome, adhesions, and quality of life after laparoscopic and open surgical therapies for acute abdomen: follow-up of a prospective trial.

机译:腹腔镜和开放式手术治疗急性腹部术后的长期结果,粘连和生活质量:一项前瞻性试验的随访。

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BACKGROUND: The objective of this study was to determine the long-term outcome of laparoscopic and open therapies for acute abdomen, and to assess the patients postoperative quality of life, with special attention to adhesions. METHODS: A follow-up study was conducted from June through December 2001 of a case-control trial of laparoscopic and open surgical treatment in patients with acute abdomen. Mean (median) duration of follow-up was 35.9 months (32.5) for the laparoscopic group (L) and 40.7 months (38.5) for the open group (O). A total of 284 (92%) of the original 310 study patients (108 L and 202 O) were contacted. Twenty-eight (9%) were confirmed to be dead. From the remaining 256 patients (131 men and 125 women, mean age [+/- SD] 38.9 +/- 19.9 years), we enrolled 153(67 L and 91 O) in the follow-up. The main outcome measures were frequency of relapse requiring treatment, frequency of reoperations, incidence of adhesion ileus and incisional hernia, distant morbidity and mortality, satisfaction with therapy, and Gastrointestinal Quality of Life Index (GQLI) scores. RESULTS: The morbidity and mortality rates, readmission rates, incisional hernia rates, and scores for long-term quality of life were the same in both groups. The reoperation rate was significantly higher among L patients, but there were significantly fewer episodes of adhesion ileus in this group. Patient satisfaction was 85% in the L group and 73% in the O group (p = NS). CONCLUSIONS: The laparoscopic treatment of patients with acute abdomen offers an outcome comparable to that achieved with the open approach. There were fewer episodes of adhesion ileus in laparoscopic patients. Consequently, the operative treatment of acute abdomen patients by laparoscopy can be recommended.
机译:背景:这项研究的目的是确定腹腔镜和开放治疗急性腹部的长期结果,并评估患者的术后生活质量,特别注意粘连。方法:从2001年6月至2001年12月进行了一项针对腹腔镜和开放性手术治疗急性腹部患者的病例对照试验的随访研究。腹腔镜组(L)的平均(中位)随访时间为35.9个月(32.5),开放组(O)的平均随访时间为40.7个月(38.5)。最初接触的310名研究患者(108 L和202 O)中总共有284(92%)人接触过。确认有28人(9%)死亡。在剩余的256位患者(131位男性和125位女性,平均年龄[+/- SD] 38.9 +/- 19.9岁)中,我们纳入了153例患者(67 L和91 O)。主要结局指标为需要治疗的复发频率,再次手术的频率,粘连性肠梗阻和切口疝的发生率,远处的发病率和死亡率,对治疗的满意度以及胃肠道生活质量指数(GQLI)得分。结果:两组的发病率和死亡率,再入院率,切开疝的发生率以及长期生活质量得分均相同。 L组患者的再手术率显着更高,但该组粘连性肠梗塞的发作率明显降低。 L组患者满意度为85%,O组患者满意度为73%(p = NS)。结论:腹腔镜治疗急性腹部患者提供的结果与开放方法相当。腹腔镜患者较少发生粘连性肠梗阻。因此,可以建议通过腹腔镜手术对急性腹部患者进行手术治疗。

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